The International Journal of Antimicrobial Agents provides comprehensive and up-to-date peer reviewed reference information on the physical, pharmacological, in vitro and clinical properties of individual antimicrobial agents (antiviral agents, antiparasitic agents, antibacterial agents, antifungal agents, immunotherapeutic agents, etc.). In addition, the journal signals new trends and developments in the field through highly authoritative review articles on antimicrobial agents, immunomodulators and immunotherapy. Special attention is given to articles providing insight into the problems of antimicrobial resistance, local as well as world-wide, both in the hospital and in the community. Papers on the underlying mechanisms and on immunomodulating agents are also welcome. Both solicited reviews by top experts in the mentioned fields and high-quality original research papers are published. Additional information on the ISC and its activities can be found at the ISC Web site at: http://www.ischemo.org