Kidney International (KI) is undergoing exciting changes to be seen in the first 2006 issue. The new KI offers features with premier benefits for both readers and authors. Here you will find some of the most cited original articles in nephrology, sharply focused reviews, latest imaging techniques, controversial discussions and much more. The redesigned journal increases its frequency to 24 issues per year, and together, the new Editorial team, ISN, and NPG will offer readers the very best of nephrology. Kidney International devotes itself to renal research. It aims to inform the renal researcher and the practicing nephrologist on all aspects of renal research. These include: The latest clinical studies on emerging developments in renal medicine; The highest level of original research studies in clinical and basic renal research; In each issue some of these articles will be highlighted by commentaries that aim to put these studies in the appropriate context. These will form a research tool for clinical and basic investigators; Editorials that highlight important issues in international nephrology; Nephrology sans Frontieres - occasional short articles that discuss matters of local interest to nephrologists around the world, but which we feel need to be known by nephrologists world-wide; Minireviews on hot topics and in depth reviews about major issues in renal research; Controversial discussions on renal therapeutics or diagnosis written by two opposing authorities; State-of-the-Art teaching materials including The Renal Consults and clinico-pathological conferences where eminent clinicians discuss difficult or interesting cases illustrated by multiple pathology, imaging studies and charts; Nephrology Images which are presentations of interesting images in renal pathology, radiology chosen for their illustrative nature or simply for their esthetic qualities; Issues of importance to the international renal community including the politics of funding; of organ transplantation, of adequacy of dialysis, of world-wide affordability of end stage renal care and many other topical issues; Journal Club are synopses that bring you the latest research highlights from across a wide spectrum of journals in fields relevant to renal research.