One of the world's leading medical journals, the NEJM publishes original research and interpretive articles in major aspects of medicine: its science, its art and practice, and its position in today's society. Each week, The Journal presents major, previously unpublished research results, clinical findings, updates and opinions.

Our mission is to bring physicians the best research and information at the intersection of biomedical science and clinical practice and to present this information in understandable and clinically useful formats that inform health care delivery and improve patient outcomes.

John Collins Warren, a Boston physician and scholar, collaborated in 1811 with colleague James Jackson to establish the first medical journal in New England, publishing the first quarterly edition of the New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science (Boston) in January of 1812.

In 1921, the journal merged with the Boston Medical Intelligencer to become the Boston Medical and Surgical Journal; it also began weekly publication that year and was purchased by the Massachusetts Medical Society.

Renamed to the New England Journal of Medicine in 1928, the journal is known for many firsts in medicine, including the first to publish a full description of spinal disk rupture (1934), the first to document success in treating early childhood leukemia (1948), and the first American medical journal to receive the Polk Award for journalistic excellence.