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Research on Beers Criteria and STOPP/START Criteria based on the FDA FAERS database

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (8)

Purpose Inappropriate medication criteria for the elderly have played an important role in ensuring the safety of medications for the elderly. Too few......

The efficacy and safety of rivaroxaban in coronary artery disease patients with heart failure and sinus rhythm: a systematic review and meta-analysis

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (10)

Purpose To explore the efficacy and safety of rivaroxaban in patients with coronary artery disease (CAD), heart failure (HF) and sinus rhythm (SR). Me......

Incidence risk of PD-1/PD-L1-related pneumonia and diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis of randomized controlled trials

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (8)

Background Programmed cell death-1 (PD-1) and programmed cell death ligand-1(PD-L1) inhibitor therapy have been approved for the treatment of many can......

A cross-sectional study of chemotherapy-related AKI

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (10)

Purpose This study aims to detail the characteristics of chemotherapy-related acute kidney injury (CR-AKI) and investigate its effect on patient outco......

Safety and efficacy of new oral anticoagulants compared to those of warfarin in AF patients with cancer: a meta-analysis of randomized clinical trials and observational studies

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (6)

Background Data on the efficacy and safety of nonvitamin K antagonist oral anticoagulants (NOACs) in atrial fibrillation (AF) patients with cancer are......

The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose-corrected trough concentration in the early period after liver transplantation

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Purpose To explore the relationship between rs2291075 polymorphism in SLCO1B1 gene, which encodes an influx transmembrane protein transporter, and tac......

Population pharmacokinetics of unbound valproic acid in pediatric epilepsy patients in China: a protein binding model

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Purpose The purpose of this study was to establish a protein binding model of unbound valproic acid (VPA) based on Chinese pediatric patients with epi......

Application of physiologically based pharmacokinetic modeling to predict the pharmacokinetics of telavancin in obesity with renal impairment

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Purpose U.S. Food and Drug Administration (FDA) recommended telavancin dosing is based on total body weight (TBW) but lacks adjusted regimens for obes......

Calcineurin inhibitor-associated new-onset diabetes mellitus in chronic kidney disease treatment: a 4-year single-center cross-sectional study in China

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Purpose To identify the risk factors of calcineurin inhibitor (CNI)-associated new-onset diabetes mellitus (NODM) in chronic kidney disease (CKD) trea......

Pharmacogenetics of tamoxifen therapy in Asian populations: from genetic polymorphism to clinical outcomes

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Background Compared with western countries, Asian breast cancer patients have unique pathological and biological characteristics. Most of them are pre......

Randomized, placebo-controlled trial of orally administered vitamin K1 for warfarin-associated coagulopathy in Chinese patients with mechanical heart valves

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ()

Purpose Warfarin-associated coagulopathy commonly occurs in patients undergoing treatment with this anticoagulant. This trial aimed to determine the e......

The impacts of race and regimens on the efficacy and safety of paclitaxel and platinum combination treatment for patients with advanced non-small cell lung cancer

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021; 77 (5)

Purpose Paclitaxel-platinum chemotherapy is the first-line treatment for advanced non-small cell lung cancer (NSCLC) patients. This study quantitative......

Population pharmacokinetics and dose optimization of ceftriaxone for children with community-acquired pneumonia

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2020; 76 (11)

Purpose To assess ceftriaxone population pharmacokinetics in a large pediatric population and describe the proper dose for establishing an optimized a......

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