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Inhibition of Staphylococcus aureus and biofilm formation by the anthelminthic drug, triclabendazole

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)

Triclabendazole (TBD) has been widely used in the treatment of helminthic infection. The anti-biofilm activity and antibacterial mechanism of TBD agai......

JIF:2.308

Marinacarboline glucuronide, a new member of beta-carboline alkaloids from sponge-derived actinomycete Actinoalloteichus cyanogriseus LHW52806

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)

A new member of beta-carboline alkaloids, Marinacarboline glucuronide (1), along with nine known compounds (2-10), were isolated from static liquid fe......

JIF:2.308

Penicixanthene E, a new xanthene isolated from a mangrove-derived fungus Penicillium sp.

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)

One new xanthene derivative, named penicixanthene E (1), together with one known compound 2, was isolated from the EtOAc extract of the endophytic fun......

JIF:2.308

In vitro activity and adaptation strategies of eravacycline in clinical Enterococcus faecium isolates from China

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)

Eravacycline (Erava) is a synthetic fluorocycline with potent antimicrobial activity against a wide range of Gram-positive bacteria. This study aimed ......

JIF:2.308

Metabolic response of Lactobacillus acidophilus exposed to amoxicillin

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)

Drug-induced diarrhea is a common adverse drug reaction, especially the one caused by the widespread use of antibiotics. The reduction of probiotics i......

JIF:2.308

Halovirs I-K, antibacterial and cytotoxic lipopeptaibols from the plant pathogenic fungus Paramyrothecium roridum NRRL 2183

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)

Three new lipopeptaibols, halovirs I-K (1-3), were isolated from the solid culture of the phytopathogenic fungus Paramyrothecium roridum NRRL 2183. Th......

JIF:2.308

Evaluation of a novel inhibitor of aspartate semialdehyde dehydrogenase as a potent antitubercular agent against Mycobacterium tuberculosis

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (6)

The in vitro activity of IMB-XMA0038, a novel inhibitor targeting Mycobacterial tuberculosis (Mtb) aspartate semialdehyde dehydrogenase, was evaluated......

JIF:2.308

Nigirpexin E, a new azaphilone derivative with anti-tobacco mosaic virus activity from soil-derived fungus Trichoderma afroharzianum LTR-2

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (2)

A new compound classified as one new azaphilone derivative, nigirpexin E (1), was obtained from the soil-derived fungus Trichoderma afroharzianum LTR-......

JIF:2.308

Discovery of novel septacidin congeners from a high yield heterologous expression strain Streptomyces albus 1597

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (3)

Septacidin is an adenine nucleoside antibiotic with antifungal and antitumor activities. During the efforts to construct a better septacidin producer,......

JIF:2.308

Isatropolone/isarubrolone C-m from Streptomyces with biological activity of inducing incomplete autophagy

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (12)

Isatropolones/isarubrolones are Streptomyces secondary metabolites featuring a tropolone ring in the pentacyclic scaffolds of these molecules. They ar......

JIF:2.308

Triclosan targeting of gut microbiome ameliorates hepatic steatosis in high fat diet-fed mice

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (6)

Antibiotic use provides a promising strategy for the treatment of non-alcoholic fatty liver disease (NAFLD) by regulating the gut microbiota compositi......

JIF:2.308

Methimazole and alpha-lipoic acid as metallo-beta-lactamases inhibitors

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)

The emergence of bacterial resistance poses a serious threat to public health. One of the most important resistance mechanisms against beta-lactam ant......

JIF:2.308

Comparison of antibacterial activities and resistance mechanisms of omadacycline and tigecycline against Enterococcus faecium

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (8)

This study aims to compare the antimicrobial activity of omadacycline with tigecycline against clinical isolates of Enterococcus faecium and investiga......

JIF:2.308

Two new 22-membered macrolides from Streptomyces sp. HU210

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (11)

Two new 22-membered macrolide metabolites, phthoramycins B (1) and C (2), were isolated from the fermentation broth of Streptomyces sp. HU210. Their s......

JIF:2.308

Pestalotinones A-D, new benzophenone antibiotics from endophytic fungus Pestalotiopsis trachicarpicola SC-J551

期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (4)

Four new pestalone-type benzophenones, pestalotinones A-D (1-4), along with six known congeners, pestalone, pestalone E-F, SB87-Cl, SB87-H, and pestal......

JIF:2.308

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