期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)
Triclabendazole (TBD) has been widely used in the treatment of helminthic infection. The anti-biofilm activity and antibacterial mechanism of TBD agai......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)
A new member of beta-carboline alkaloids, Marinacarboline glucuronide (1), along with nine known compounds (2-10), were isolated from static liquid fe......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)
One new xanthene derivative, named penicixanthene E (1), together with one known compound 2, was isolated from the EtOAc extract of the endophytic fun......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (9)
Eravacycline (Erava) is a synthetic fluorocycline with potent antimicrobial activity against a wide range of Gram-positive bacteria. This study aimed ......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)
Drug-induced diarrhea is a common adverse drug reaction, especially the one caused by the widespread use of antibiotics. The reduction of probiotics i......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)
Three new lipopeptaibols, halovirs I-K (1-3), were isolated from the solid culture of the phytopathogenic fungus Paramyrothecium roridum NRRL 2183. Th......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (6)
The in vitro activity of IMB-XMA0038, a novel inhibitor targeting Mycobacterial tuberculosis (Mtb) aspartate semialdehyde dehydrogenase, was evaluated......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (2)
A new compound classified as one new azaphilone derivative, nigirpexin E (1), was obtained from the soil-derived fungus Trichoderma afroharzianum LTR-......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (3)
Septacidin is an adenine nucleoside antibiotic with antifungal and antitumor activities. During the efforts to construct a better septacidin producer,......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (12)
Isatropolones/isarubrolones are Streptomyces secondary metabolites featuring a tropolone ring in the pentacyclic scaffolds of these molecules. They ar......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (6)
Antibiotic use provides a promising strategy for the treatment of non-alcoholic fatty liver disease (NAFLD) by regulating the gut microbiota compositi......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (5)
The emergence of bacterial resistance poses a serious threat to public health. One of the most important resistance mechanisms against beta-lactam ant......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (8)
This study aims to compare the antimicrobial activity of omadacycline with tigecycline against clinical isolates of Enterococcus faecium and investiga......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (11)
Two new 22-membered macrolide metabolites, phthoramycins B (1) and C (2), were isolated from the fermentation broth of Streptomyces sp. HU210. Their s......
期刊: JOURNAL OF ANTIBIOTICS, 2022; 75 (4)
Four new pestalone-type benzophenones, pestalotinones A-D (1-4), along with six known congeners, pestalone, pestalone E-F, SB87-Cl, SB87-H, and pestal......