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Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review

期刊: MITOCHONDRION, 2022; 64 ()

Mitochondrial permeability transition pore (mPTP) is a channel that opens at the inner mitochondrial membrane under conditions of stress. Sirtuin 3 (S......

JIF:3.717

Phenotypes and genotypes of mitochondrial diseases with mtDNA variations in Chinese children: A multi-center study

期刊: MITOCHONDRION, 2022; 62 ()

Mitochondrial DNA (mtDNA) associated mitochondrial diseases hold a crucial position but comprehensive and systematic studies are relatively rare. Amon......

JIF:3.717

Epigenetic control of mitochondrial fission enables hepatic stellate cells activation in liver fibrosis via PGC-1 alpha-Drp1 pathway

期刊: MITOCHONDRION, 2022; 66 ()

Although excessive mitochondrial fission is linked to cell activation, its significance in hepatic stellate cells (HSCs) activation and liver fibrosis......

JIF:3.717

Epigenetic control of mitochondrial fission enables hepatic stellate cells activation in liver fibrosis via PGC-1 alpha-Drp1 pathway

期刊: MITOCHONDRION, 2022; 66 ()

Although excessive mitochondrial fission is linked to cell activation, its significance in hepatic stellate cells (HSCs) activation and liver fibrosis......

JIF:3.717

Insight of the role of mitochondrial calcium homeostasis in hepatic insulin resistance

期刊: MITOCHONDRION, 2022; 62 ()

Due to the rapid rise in the prevalence of chronic metabolic disease, more and more clinicians and basic medical researchers focus their eyesight on i......

JIF:3.717

Precise annotation of Drosophila mitochondrial genomes leads to insights into AT-rich regions

期刊: MITOCHONDRION, 2022; 65 ()

In the present study, we performed precise annotation of Drosophila melanogaster, D. simulans, D. grimshawi, Bactrocera oleae mitochondrial (mt) genom......

JIF:3.717

Regulation of mitochondrial network homeostasis by O-GlcNAcylation

期刊: MITOCHONDRION, 2022; 65 ()

O-GlcNAcylation, a ubiquitous post-translational modification, rapidly modulates protein activity through the reversible addition and removal of O-Glc......

JIF:3.717

Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes

期刊: MITOCHONDRION, 2022; 65 ()

Microvascular protection is the main mechanism of metformin against diabetic complications. Cardiac microvascular endothelial cells (CMECs) are the ba......

JIF:3.717

Polymorphisms and haplotype of mitochondrial DNA D-loop region are associated with polycystic ovary syndrome in a Chinese population

期刊: MITOCHONDRION, 2021; 57 ()

Polymorphisms in mitochondrial DNA (mtDNA) have been linked to a range of diseases. Here we investigate the relationship between mtDNA D-loop region p......

Vessel flow void sign and hyperintense vessel sign on FLAIR images distinguish between MELAS and AIS

期刊: MITOCHONDRION, 2021; 58 ()

Objective: This study aimed to evaluate the sensitivity and specificity of the vessel signs, including the Vessel Flow Void Sign (VFVS) and the Hyperi......

Mitophagy pathways and Alzheimer's disease: From pathogenesis to treatment

期刊: MITOCHONDRION, 2021; 59 ()

Alzheimer's disease (AD) is an age-dependent, incurable mental illness that is associated with the accumulation of aggregates of amyloid-beta (A beta)......

MicroRNA-338 inhibition protects against focal cerebral ischemia and preserves mitochondrial function in vitro in astrocytes and neurons via COX4I1

期刊: MITOCHONDRION, 2021; 59 ()

Brain-enriched microRNA-338 (miR-338) is known to play a central role in brain mitochondrial function, however the role of miR-338 in stroke injury re......

Prothymosin alpha promotes colorectal carcinoma chemoresistance through inducing lipid droplet accumulation

期刊: MITOCHONDRION, 2021; 59 ()

Colorectal cancer (CRC) affects millions of people worldwide. Chemoresistance seriously impairs the therapeutic effects. Lipid droplets (LDs) abnormal......

Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice

期刊: MITOCHONDRION, 2021; 58 ()

Type 2 Diabetes mellitus (T2DM) has become a major public health issue associated with a high risk of late-onset Alzheimer's disease (LOAD). Mitochond......

Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 1

期刊: MITOCHONDRION, 2021; 59 ()

The protective effect of intermittent hypoxia (IH) preconditioning against oxidative injury in hepatic cells was investigated and the involvement of t......

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