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Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression

期刊: DEVELOPMENTAL CELL, 2022; 57 (7)

The switch from mitosis to meiosis ensures the successive formation of gametes. However, it remains unclear how meiotic initiation occurs within the c......

JIF:7.602

Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption

期刊: DEVELOPMENTAL CELL, 2022; 57 (20)

Gasdermin D (GSDMD)-mediated pyroptosis induces immunogenic cell death and promotes inflammation. However, the functions of GSDMD in tissue homeostasi......

JIF:7.602

Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis

期刊: DEVELOPMENTAL CELL, 2022; 57 (5)

As sessile organisms, plants are highly sensitive to environmental stresses. In response to stresses, globally repressed translation initiation leads ......

JIF:7.602

Two sensory neurons coordinate the systemic mitochondrial stress response via GPCR signaling in C. elegans

期刊: DEVELOPMENTAL CELL, 2022; 57 (21)

Mitochondrial perturbations within neurons communicate stress signals to peripheral tissues, coordinating organismal-wide mitochondrial homeostasis fo......

JIF:7.602

Nitrate availability controls translocation of the transcription factor NAC075 for cell-type-specific reprogramming of root growth

期刊: DEVELOPMENTAL CELL, 2022; 57 (23)

Plant root architecture flexibly adapts to changing nitrate (NO3-) availability in the soil; however, the underlying molecular mechanismof this adapti......

JIF:7.602

Essential role of MESP1-RING1A complex in cardiac differentiation

期刊: DEVELOPMENTAL CELL, 2022; 57 (22)

Heart development is controlled by a complex transcriptional network composed of transcription factors and epigenetic regulators. Mutations in key dev......

JIF:7.602

Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse

期刊: DEVELOPMENTAL CELL, 2022; 57 (24)

Spinal cord development is precisely orchestrated by spatiotemporal gene regulatory programs. However, the underlying epigenetic mechanisms remain lar......

JIF:7.602

Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

期刊: DEVELOPMENTAL CELL, 2022; 57 (14)

Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling niche. Overactivation of Hedgehog signaling in the nic......

JIF:7.602

Single-cell analysis of human testis aging and correlation with elevated body mass index

期刊: DEVELOPMENTAL CELL, 2022; 57 (9)

Aging men display reduced reproductive health; however, testis aging is poorly understood at the molecular and genomic levels. Here, we utilized singl......

JIF:7.602

The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves

期刊: DEVELOPMENTAL CELL, 2022; 57 (10)

Understanding the complex functions of plant leaves requires a thorough characterization of discrete cell features. Although single-cell gene expressi......

JIF:7.602

Root twisting drives halotropism via stress-induced microtubule reorientation

期刊: DEVELOPMENTAL CELL, 2022; 57 (20)

Plants have evolved signaling mechanisms that guide growth away from adverse environments that can cause yield losses. Root halotropism is a sodium-sp......

JIF:7.602

High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

期刊: DEVELOPMENTAL CELL, 2022; 57 (10)

Drosophila has long been a successful model organism in multiple biomedical fields. Spatial gene expression patterns are critical for the understandin......

JIF:7.602

Sulfenylation of ENOLASE2 facilitates H2O2-conferred freezing tolerance in Arabidopsis

期刊: DEVELOPMENTAL CELL, 2022; 57 (15)

H2O2 affects the expression of genes that are involved in plant responses to diverse environmental stresses; however, the underlying mechanisms remain......

JIF:7.602

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