期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 163 ()
Vascular disease is the prime determinant to cardiovascular morbidities and mortalities, which comprises the early vascular damage and subsequent card......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 164 ()
Effects of hypertrophic challenge on small-conductance, Ca2+-activated K+ (SK2) channel expression were explored in intact murine hearts, isolated ven......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 173 ()
Epigenetic regulation such as histone modification is implicated in the pathogenesis of myocardial ischemia/ reperfusion injury (MIRI). Lysine-specifi......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 164 ()
The global propagation of SARS-CoV-2 leads to an unprecedented public health emergency. Despite that the lungs are the primary organ targeted by COVID......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 167 ()
Neovascularization of the ischemic myocardium following infarction is vital for the survival of cardiomyocytes and prevention of heart failure. Howeve......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 168 ()
Vascular endothelium maintains vascular homeostasis through liberating a spectrum of vasoactive molecules, both protective and harmful regulators of v......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 173 ()
Autophagy flux is impaired during myocardial ischemia/reperfusion (M-I/R) via the accumulation of autopha-gosome and insufficient clearance, which exa......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 166 ()
Stem cell therapy may be a promising option for the treatment of vascular diseases. In recent years, significant progress has been made in stem cell r......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 169 ()
Aortic aneurysms, including thoracic aortic aneurysms and abdominal aortic aneurysms, are life-threatening macrovascular diseases with high mortality.......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 167 ()
Rationale: Mineralocorticoid receptor (MR) antagonists have been clinically used to treat heart failure. However, the underlying cellular and molecula......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 171 ()
Aortic aneurysm and dissection (AAD) is a life-threatening medical condition associated with high morbidity and mortality rates. Important mechanisms ......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 172 ()
Inflammation plays a central role in the development of heart failure. Prostaglandin E2 (PGE2) is a key mediator of the inflammatory process in the ca......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 173 ()
With its complicated pathobiology and pathophysiology, heart failure (HF) remains an increasingly prevalent epidemic that threatens global human healt......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 169 ()
Chemokine receptor CXCR4 plays a crucial role in leukocyte recruitment and inflammation regulation to influence tissue repair in ischemic diseases. He......
期刊: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 168 ()
Primary cardiomyocytes (CMs) are invaluable materials used to study in vitro cardiac physiology and pathophysiology. However, there is still a lack of......