期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
In recent years, the most widely distributed eukaryotic messenger RNA (mRNA) modification, N6-methyladenosine (m6A), has received a large amount of in......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
After it was discovered approximately 40 years ago, carbohydrate antigen 125 (CA125) became the most widely used and concerning biomarker in ovarian c......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
Cancer is a major cause of morbidity and mortality worldwide due to its ability to evade immune surveillance and metastasize from its origin to a seco......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
Gynecological cancers are characterized by a high mortality rate when chemoresistance develops. Autophagy collaborates with apoptosis and participates......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Accumulated evidence from genetically modified cell and animal models indicates that centrosome amplification (CA) can initiate tumorigenesis with met......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Reversible phosphorylation of proteins, controlled by kinases and phosphatases, is involved in various cellular processes. Dual-specificity phosphatas......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
The DNA damage response (DDR) is critical for the maintenance of genomic stability by sensing DNA damage, regulating cell cycle and initiating DNA rep......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Molecular targeted therapy of cancer has always been the focus of clinicians. Among those therapeutic targets, the human epidermal growth factor recep......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Apoptosis deficiency is one of the most important features observed in neoplastic diseases. The Bcl-2 family is composed of a subset of proteins that ......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Mitochondria, well recognized as the "powerhouse" of cells, are maternally inherited organelles with bacterial ancestry that play essential roles in a......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Platinum compounds (cisplatin and carboplatin) represent the most active anticancer agents in clinical use both of lung cancer in mono-and combination......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1875 (2)
Carbohydrate antigen 19-9 (CA19-9) is the best validated biomarker and an indicator of aberrant glycosylation in pancreatic cancer. CA19-9 functions a......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
In cancer cells, tumor suppressor proteins loss-of-function are usually the result of genetic mutations. Protein Phosphatase 2A is a tumor suppressor ......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous myeloid cell population characterized by pro-tumoral functions in the tumor immune networ......
期刊： BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2021; 1876 (1)
Increasing evidence shows that numerous cancer-testis antigens (CTAs) are uniquely overexpressed in various types of cancer and most CTAs are oncogeni......
