期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (6)
EGFR-targeted chimeric antigen receptor (CAR) T cells are potent and specific in suppressing the growth of triple-negative breast cancer (TNBC) in vit......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (9)
Chimeric antigen receptor (CAR) T-cell therapies that target either CD19 or CD22 alone have potent antilymphoma effects. However, antigen escape-media......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (4)
Several landmark predinical studies have shown an association between the gut microbiota and the effectiveness of immunotherapy for cancer. These stud......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (9)
T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is a checkpoint receptor that mediates both T-cell and natural killer (NK)-cell exhaustion in t......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (8)
Immune cell infiltration is important for predicting the clinical outcomes of colorectal cancer. Integrin beta 7 (ITGB7), which is expressed on the su......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (7)
Tumor cells can evade immune surveillance and immune killing during the emergence of endocrine therapy resistance in prostate cancer, but the mechanis......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (4)
Immunologic checkpoint blockade has been proven effective in a variety of malignancies. However, high rates of resistance have substantially hindered ......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (9)
Although chimeric antigen receptor T (CART)-cell therapy has been successful in treating certain hematologic malignancies, wider adoption of CART-cell......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (9)
Chronic inflammation is a key driver for colitis-associated colorectal cancer. 5-hydroxytryptarnine (5-HT), a neurotransmitter, has been reported to p......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (8)
Single-cell sequencing opens a new era for the investigation of tumor immune microenvironments (TIME). However, at single-cell resolution, a pan-cance......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (3)
A number of staging systems have been developed to predict clinical outcomes in hepatocellular carcinoma (HCC). However, no general consensus has been......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (1)
Metabolism is reprogrammed in cancer to fulfill the demands of malignant cells for cancer initiation and progression. Apart from its effects within ca......
期刊： CANCER IMMUNOLOGY RESEARCH, 2021; 9 (3)
Conventional dendritic cells (cDC) play a central role in T-cell antitumor responses. We studied the significance of Notch-regulated DC immune respons......
期刊： CANCER IMMUNOLOGY RESEARCH, 2020; 8 (2)
CMTM6, a regulator of PD-L1 expression, also modulates tumor immunity. Little is known about the function of CMTM6 and its mechanism of action in head......
