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Serum superoxide dismutase activity: a sensitive, convenient, and economical indicator associated with the prevalence of chronic type 2 diabetic complications, especially in men

期刊: FREE RADICAL RESEARCH, 2021; 55 (3)

To investigate the relationship between serum superoxide dismutase (SOD) activity and the presence of chronic complications in patients with type 2 di......

Iron metabolism: an emerging therapeutic target underlying the anti-cancer effect of quercetin

期刊: FREE RADICAL RESEARCH, 2021; 55 (3)

Iron, an essential micronutrient for all kinds of cells, is essential for the balance of body internal environment. Notably, cancer cells exhibit a st......

4-Hydroxy-2-nonenal, a lipid peroxidation product, as a biomarker in diabetes and its complications: challenges and opportunities

期刊: FREE RADICAL RESEARCH, ; ()

Over 30 million Americans are diagnosed with diabetes and this number is only expected to increase. There are various causes that induce complications......

Growth differentiation factor 11 mitigates cardiac radiotoxicity via activating AMPK alpha

期刊: FREE RADICAL RESEARCH, ; ()

Cardiac radiotoxicity largely impedes the therapeutic benefits of radiotherapy to malignancies. Growth differentiation factor 11 (GDF11) is implicated......

BSC2 enhances cell resistance to AmB by inhibiting oxidative damage in Saccharomyces cerevisiae

期刊: FREE RADICAL RESEARCH, 2020; 54 (4)

Amphotericin B has been the gold standard for the treatment of invasive mycosis for many years. Its resistance mechanisms are reported to be mainly re......

Edaravone attenuates myocyte apoptosis through the JAK2/STAT3 pathway in acute myocardial infarction

期刊: FREE RADICAL RESEARCH, 2020; 54 (5)

Basic and clinical studies have demonstrated that the free radical scavenger edaravone has cytoprotective effects on acute myocardial infarction (AMI)......

Silencing of long non-coding RNA LINC00520 promotes radiosensitivity of head and neck squamous cell carcinoma cells

期刊: FREE RADICAL RESEARCH, 2020; 54 (4)

Aberrant expression of LINC00520 has been identified in head and neck squamous carcinoma (HNSCC). However, its function in the radiosensitivity of HNS......

MicroRNA-326 prevents sepsis-induced acute lung injury via targeting TLR4

期刊: FREE RADICAL RESEARCH, 2020; 54 (6)

Unrestrained inflammation provokes oxidative stress and contributes to the development of sepsis-induced acute lung injury (ALI). MicroRNA-326 (miR-32......

Labile iron affects pharmacological ascorbate-induced toxicity in osteosarcoma cell lines

期刊: FREE RADICAL RESEARCH, 2020; 54 (6)

Vitamin C and iron are both important nutrients for humans and involved in several physiological processes. The biological activities of vitamin C and......

Coumestrol ameliorates doxorubicin-induced cardiotoxicity via activating AMPK alpha

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Doxorubicin (DOX) acts as the cornerstone in multiple tumour chemotherapy regimens, however, its clinical application is often impeded due to the indu......

Negative association between antioxidant vitamin intake and non-alcoholic fatty liver disease in Chinese non-diabetic adults: mediation models involving superoxide dismutase

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

We aimed to explore the association between antioxidant vitamin intake, oxidative stress related markers and non-alcoholic fatty liver disease (NAFLD)......

Up-regulation of LncRNA NEAT1 induces apoptosis of human placental trophoblasts

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

The trophoblast apoptosis induced by placental oxidative stress is a contributor to the pathological development of preeclampsia (PE), whereas the mol......

Study of the controversial resveratrol that interact with the endogenous glutathione thiyl radical in cancer cells

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Found in various natural food products, manyin vitroevidence indicated that resveratrol (RES) has been linked to neuroprotective and cardioprotective ......

Effects of GST null genotypes on individual susceptibility to atherosclerotic cardiovascular diseases: a meta-analysis

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Some genetic association studies tried to investigate potential associations between glutathione S-transferase (GST) null genotypes and atheroscleroti......

Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis

期刊: FREE RADICAL RESEARCH, 2020; 54 (10)

Ischaemia-reperfusion injury (IRI) is closely related to cardiovascular disease (CVD), which is the leading cause of death and disability. Exosomes ap......

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