期刊: CANCER GENE THERAPY, 2022; 29 (1)
microRNAs (miRNAs) have been revealed to participate in some oral cancers and are proved to be effective. In the present study, we tried to explore th......
期刊: CANCER GENE THERAPY, 2022; 29 (1)
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the ......
期刊: CANCER GENE THERAPY, 2022; 29 (3-4)
Long non-coding RNAs (lncRNAs) were recently recognized to vitally function in a variety of cancer cellular events, including epithelial-mesenchymal t......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Autophagy is the predominant self-eating catabolic pathway activated in response to nutrient starvation and hypoxia within the microenvironment of var......
期刊: CANCER GENE THERAPY, 2022; 29 (11)
Drug resistance is a key factor in the treatment failure of acute myeloid leukemia (AML). Nuclear factor E2-related factor 2 (Nrf2) plays a crucial ro......
期刊: CANCER GENE THERAPY, 2022; 29 (7)
N-6-methyladenosine (m(6)A) RNA methylation and its associated methyltransferase METTL3 play an important role in tumorigenesis of a series of tumors.......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Alpha-synuclein (alpha-syn), encoded by the SNCA gene, is a major participant in the pathophysiology of Parkinson's disease (PD). Its functions have b......
期刊: CANCER GENE THERAPY, 2022; 29 (11)
The homeobox gene family encodes transcription factors that are essential for cell growth, proliferation, and differentiation, and its dysfunction is ......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
The incidence of breast cancer (BC) has been increasing each year, and BC is now the most common malignant tumor in women. Among the numerous BC subty......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Macrophages plays a vital role in the development of non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), but the polarization of ......
期刊: CANCER GENE THERAPY, 2022; 29 (10)
Alternative splicing (AS) is a gene regulatory mechanism that drives protein diversity and dysregulation of AS plays a significant role in tumorigenes......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Endometrial cancer (EC) is a group of epithelial malignant tumors that occur in the endometrium. The specific pathogenesis is not revealed, hence, the......
期刊: CANCER GENE THERAPY, 2022; 29 (10)
Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to sup......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Somatic copy number alterations (SCNA), which are widespread in cancer, can predict the efficacy of immune checkpoint inhibitors in non-small-cell lun......
期刊: CANCER GENE THERAPY, 2022; 29 (11)
The Apoptosis Stimulating Protein of p53 2 (ASPP2) is a heterozygous insufficient tumor suppressor; however, its molecular mechanism(s) in tumor suppr......