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Efficacy of radiotherapy combined with immune checkpoint inhibitors in patients with melanoma: a systemic review and meta-analysis

期刊: MELANOMA RESEARCH, 2022; 32 (2)

The purpose of this study is to review the efficacy of radiotherapy combined with immune checkpoint inhibitors (ICIs) in the treatment of melanoma and......

JIF:2.871

Efficacy and safety of angiogenesis inhibitors in melanoma: a meta-analysis of seven randomized controlled trials

期刊: MELANOMA RESEARCH, 2022; 32 (3)

Little is known about the efficacy and safety of angiogenesis inhibitor therapy in patients with melanoma. The objective of this study was to assess t......

JIF:2.871

LS-007 inhibits melanoma growth via inducing apoptosis and cell cycle arrest and regulating macrophage polarization

期刊: MELANOMA RESEARCH, 2022; 32 (6)

LS-007, an inhibitor of cyclin-dependent kinase 9 (CDK9), exhibits potential antitumor activity against chronic lymphocytic leukemia and ovarian cance......

JIF:2.871

Phase II study of apatinib combined with temozolomide in patients with advanced melanoma after failure of immunotherapy

期刊: MELANOMA RESEARCH, 2022; 32 (3)

Treatment for advanced melanoma after progression on immunotherapy is limited. This phase II trial (NCT03422445) was conducted to evaluate the efficac......

JIF:2.871

LINC01063 functions as an oncogene in melanoma through regulation of miR-5194-mediated SOX12 expression

期刊: MELANOMA RESEARCH, 2022; 32 (4)

Melanoma is one of the most aggressive skin cancers and a major cause of cancer-linked deaths worldwide. As the morbidity and mortality of melanoma ar......

JIF:2.871

Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells

期刊: MELANOMA RESEARCH, 2021; 31 (4)

Early stage or localized melanoma can be surgically resected with satisfactory outcome, whereas advanced malignant melanoma responds to treatment poor......

Diagnostic and prognostic value of heat shock protein 90 alpha in malignant melanoma

期刊: MELANOMA RESEARCH, 2021; 31 (2)

Malignant melanoma is one of the most common tumours of the skin. Heat shock protein 90 alpha (HSP90 alpha) has been applied in the auxiliary diagnosi......

Clinical significance of CCNE1 copy number gain in acral melanoma patients

期刊: MELANOMA RESEARCH, 2021; 31 (4)

Copy number variations are frequently observed in cell cycle-related genes in acral melanoma. However, the clinical significance of copy number gain o......

BAP1 deletion abrogates growth and metastasis of murine cutaneous melanoma

期刊: MELANOMA RESEARCH, 2021; 31 (2)

Although germline mutations in BRCA-associated protein-1 (BAP1) predispose to cutaneous melanoma (CM), BAP1 is rarely mutated in primary CM outside th......

The role of osteopontin in the development and metastasis of melanoma

期刊: MELANOMA RESEARCH, 2021; 31 (4)

Melanoma is a highly heterogeneous tumor. The incidence of melanoma increases with age and its long-term prognosis is poor. The treatment of melanoma ......

ETS1 promoted cell growth, metastasis and epithelial-mesenchymal transition process in melanoma by regulating miR-16-mediated SOX4 expression

期刊: MELANOMA RESEARCH, 2021; 31 (4)

Melanoma is a malignant tumor with high metastasis and mortality. Epithelial-mesenchymal transition (EMT) was reported to be involved in the growth an......

Immunohistochemistry analysis reveals lysyl oxidase-like 3 as a novel prognostic marker for primary melanoma

期刊: MELANOMA RESEARCH, 2021; 31 (2)

Lysyl oxidase-like 3 (LOXL3) is an extracellular enzyme involved in the synthesis of collagen and elastin, and it has been reported to promote melanom......

Induction of T helper 17 cell response by interleukin-7 in patients with primary cutaneous melanoma

期刊: MELANOMA RESEARCH, 2021; 31 (4)

Interleukin (IL)-7 plays a vital role in proliferation and activation of T cells, however, its signaling through CD127 is impaired in T cells in cance......

Combination of radiotherapy and targeted therapy for melanoma brain metastases: a systematic review

期刊: MELANOMA RESEARCH, 2021; 31 (5)

Radiotherapy is a mainstay of efficient treatment of brain metastases from solid tumors. Immunotherapy has improved the survival of metastatic cancer ......

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