期刊: MELANOMA RESEARCH, 2022; 32 (2)
The purpose of this study is to review the efficacy of radiotherapy combined with immune checkpoint inhibitors (ICIs) in the treatment of melanoma and......
期刊: MELANOMA RESEARCH, 2022; 32 (3)
Little is known about the efficacy and safety of angiogenesis inhibitor therapy in patients with melanoma. The objective of this study was to assess t......
期刊: MELANOMA RESEARCH, 2022; 32 (6)
LS-007, an inhibitor of cyclin-dependent kinase 9 (CDK9), exhibits potential antitumor activity against chronic lymphocytic leukemia and ovarian cance......
期刊: MELANOMA RESEARCH, 2022; 32 (3)
Treatment for advanced melanoma after progression on immunotherapy is limited. This phase II trial (NCT03422445) was conducted to evaluate the efficac......
期刊: MELANOMA RESEARCH, 2022; 32 (4)
Melanoma is one of the most aggressive skin cancers and a major cause of cancer-linked deaths worldwide. As the morbidity and mortality of melanoma ar......
期刊: MELANOMA RESEARCH, 2021; 31 (4)
Early stage or localized melanoma can be surgically resected with satisfactory outcome, whereas advanced malignant melanoma responds to treatment poor......
期刊: MELANOMA RESEARCH, 2021; 31 (2)
Malignant melanoma is one of the most common tumours of the skin. Heat shock protein 90 alpha (HSP90 alpha) has been applied in the auxiliary diagnosi......
期刊: MELANOMA RESEARCH, 2021; 31 (4)
Copy number variations are frequently observed in cell cycle-related genes in acral melanoma. However, the clinical significance of copy number gain o......
期刊: MELANOMA RESEARCH, 2021; 31 (2)
Although germline mutations in BRCA-associated protein-1 (BAP1) predispose to cutaneous melanoma (CM), BAP1 is rarely mutated in primary CM outside th......
期刊: MELANOMA RESEARCH, 2021; 31 (4)
Melanoma is a highly heterogeneous tumor. The incidence of melanoma increases with age and its long-term prognosis is poor. The treatment of melanoma ......
期刊: MELANOMA RESEARCH, 2021; 31 (4)
Melanoma is a malignant tumor with high metastasis and mortality. Epithelial-mesenchymal transition (EMT) was reported to be involved in the growth an......
期刊: MELANOMA RESEARCH, 2021; 31 (2)
Lysyl oxidase-like 3 (LOXL3) is an extracellular enzyme involved in the synthesis of collagen and elastin, and it has been reported to promote melanom......
期刊: MELANOMA RESEARCH, 2021; 31 (4)
Interleukin (IL)-7 plays a vital role in proliferation and activation of T cells, however, its signaling through CD127 is impaired in T cells in cance......
期刊: MELANOMA RESEARCH, 2021; 31 (5)
Radiotherapy is a mainstay of efficient treatment of brain metastases from solid tumors. Immunotherapy has improved the survival of metastatic cancer ......
期刊: MELANOMA RESEARCH, 2020; 30 (1)
We evaluated the expression of programmed cell death protein-1 (PD-1), programmed cell death ligand 1 (PD-L1), and NY-ESO-1 antigen; the infiltration ......