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Hand-Powered Microfluidics for Parallel Droplet Digital Loop-Mediated Isothermal Amplification Assays

期刊: ACS SENSORS, 2021; 6 (8)

Droplet digital loop-mediated isothermal amplification (ddLAMP) is an important assay for pathogen detection due to its high accuracy, specificity, an......

Charge-Dependent Strategy Enables a Single Fluorescent Probe to Study the Interaction Relationship between Mitochondria and Lipid Droplets

期刊: ACS SENSORS, 2021; 6 (4)

Cooperation between organelles is essential to maintain the normal operation of the cell. A lipid droplet (LD), a dynamic organelle, is specialized in......

Wide-Range, Rapid, and Specific Identification of Pathogenic Bacteria by Surface-Enhanced Raman Spectroscopy

期刊: ACS SENSORS, 2021; 6 (8)

Sensitive, selective, rapid, and label-free detection of pathogenic bacteria with high generality is of great importance for clinical diagnosis, biose......

One-Pot Identification of BCR/ABL(p210) Transcript Isoforms Based on Nanocluster Beacon

期刊: ACS SENSORS, 2021; 6 (8)

The BCR/ABL(p210) fusion gene is a classic biomarker of chronic myeloid leukemia, which can be divided into e13a2 and e14a2 isoforms according to diff......

Development and Application of Mobile Apps for Molecular Sensing: A Review

期刊: ACS SENSORS, 2021; 6 (5)

Modern smartphone-based sensing devices are generally standalone detection platforms that can transduce signals (via the built-in USB port, audio jack......

CRISPR/Cas12a-Based Versatile Method for Checking Quantitative Polymerase Chain Reaction Samples with Cycles of Threshold Values in the Gray Zone

期刊: ACS SENSORS, 2021; 6 (5)

Quantitative polymerase chain reaction (qPCR) is widely applied in foodborne pathogen detection and diagnosis. According to the cycles of threshold (C......

Fluorescent Determination of Butyrylcholinesterase Activity and Its Application in Biological Imaging and Pesticide Residue Detection

期刊: ACS SENSORS, 2021; 6 (3)

Butyrylcholinesterase (BChE) is an essential human cholinesterase relevant to liver conditions and neurodegenerative diseases, which makes it a pivota......

Distance-Based Biosensor for Ultrasensitive Detection of Uracil-DNA Glycosylase Using Membrane Filtration of DNA Hydrogel

期刊: ACS SENSORS, 2021; 6 (6)

In the deoxyribonucleic acid (DNA) repair pathways, DNA repair enzymes have great significance for genomic integrity. As one important initiator of th......

In Vivo Brain Imaging of Amyloid-beta Aggregates in Alzheimer's Disease with a Near-Infrared Fluorescent Probe

期刊: ACS SENSORS, 2021; 6 (3)

Abnormal accumulation of amyloid-beta (A beta) has been determined to be a critical factor for the progression of Alzheimer's disease (AD), which has ......

Dual Methylation-Sensitive Restriction Endonucleases Coupling with an RPA-Assisted CRISPR/Cas13a System (DESCS) for Highly Sensitive Analysis of DNA Methylation and Its Application for Point-of-Care Detection

期刊: ACS SENSORS, 2021; 6 (6)

High-performance detection of DNA methylation possesses great significance for the diagnosis and therapy of cancer. Herein, for the first time, we pre......

Light-Addressable Square Wave Voltammetry (LASWV) Based on a Field-Effect Structure for Electrochemical Sensing and Imaging

期刊: ACS SENSORS, 2021; 6 (4)

Here, we describe a new photoelectrochemical imaging method termed light-addressable square wave voltammetry (LASWV). It measures local SWV currents a......

Quantification of Tumor Protein Biomarkers from Lung Patient Serum Using Nanoimpact Electrochemistry

期刊: ACS SENSORS, 2021; 6 (6)

Protein quantification with high throughput and high sensitivity is essential in the early diagnosis and elucidation of molecular mechanisms for many ......

Nanopore-Based Single-Molecule Investigation of DNA Sequences with Potential to Form i-Motif Structures

期刊: ACS SENSORS, 2021; 6 (7)

i-Motifs are DNA secondary structures present in cytosine-rich sequences. These structures are formed in regulatory regions of the human genome and pl......

Ionic Current Extraction in an Electrostatic-Fluid-Based Tripolar System for Ethanol Sensing

期刊: ACS SENSORS, 2021; 6 (3)

We report a microfluidics-based tripolar system to extract the ionic current the gas discharge process for gas sensing, which is structurally and flui......

Toward Quantitative Bio-sensing with Nitrogen-Vacancy Center in Diamond

期刊: ACS SENSORS, 2021; 6 (6)

The long-dreamed-of capability of monitoring the molecular machinery in living systems has not been realized yet, mainly due to the technical limitati......

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