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Axillary Paget disease with a visible satellite: a case report and literature review

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Extramammary Paget disease (EMPD) is an uncommon malignancy affecting apocrine gland-bearing skin, such as vulvar, perianal, axillary and p......

hsa_circ_001946 elevates HOXA10 expression and promotes the development of endometrial receptivity via sponging miR-135b

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Impaired endometrial receptivity is a major reason for embryo implantation failure. There's a paucity of information regarding the role of ......

LncRNA GAS5 modulates the progression of non-small cell lung cancer through repressing miR-221-3p and up-regulating IRF2

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Long non-coding RNA growth arrest specific 5 (GAS5) is a regulator in non-small cell lung cancer (NSCLC) progression. Nonetheless, the mech......

Detection of BCOR gene rearrangement in Ewing-like sarcoma: an important diagnostic tool

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background BCOR-CCNB3 sarcoma (BCS) is a group of undifferentiated small round cell sarcomas harboring the BCOR gene rearrangement which shares morpho......

An ectopic adrenocortical oncocytic adenoma in the liver highly mimicking hepatocellular carcinoma: case report and literature review

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Ectopic adrenocortical tissue is a lesion usually found incidentally during autopsy or inguinal surgery. Here, we demonstrate an extremely ......

Clinicopathological significance of primitive phenotypes in early gastric cancer with differentiated histology

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Certain gastric cancers exhibit some primitive phenotypes, which may indicate a high malignancy. In histologically differentiated early gas......

Case report: Rare myeloid sarcoma development following renal transplantation with KRAS and DNMT3A gene mutations

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background A high incidence of malignant tumors, such as post-transplant lymphoproliferative disorders (PTLD), Kaposi sarcoma, and renal cancer is com......

Giant vascular eccrine spiradenoma: the first case in the scrotum and review of the literature author

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Giant vascular eccrine spiradenoma is a rare variant of eccrine spiradenoma. It is different from the eccrine spiradenoma in its larger siz......

The pathological features of leukemic cells infiltrating the renal interstitium in chronic lymphocytic leukemia/small lymphocytic lymphoma from a large single Chinese center

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is rare in Asians, and patients with CLL/SLL seldomly undergo kidney biop......

Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at ......

Case report: histopathology and molecular pathology analysis on enteric tissue of a COVID-19 patient

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Aims Patients with COVID-19 can also have enteric symptoms. Here we analyzed the histopathology of intestinal detachment tissue from a patient with CO......

A novel tumor suppressor ASMTL-AS1 regulates the miR-1228-3p/SOX17/beta-catenin axis in triple-negative breast cancer

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background: Triple-negative breast cancer (TNBC) is a special type of breast cancer that lacks effective therapeutic targets. There is a significant n......

Enhanced expression of miR-889 forecasts an unfavorable prognosis and facilitates cell progression in hepatocellular carcinoma

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has......

T cell exhaustion is associated with the risk of papillary thyroid carcinoma and can be a predictive and sensitive biomarker for diagnosis

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background The incidence of papillary thyroid carcinoma (PTC) has been steadily increasing over the past decades. Hashimoto's thyroiditis (HT) is the ......

CCND1 copy number increase and cyclin D1 expression in acral melanoma: a comparative study of fluorescence in situ hybridization and immunohistochemistry in a Chinese cohort

期刊: DIAGNOSTIC PATHOLOGY, 2021; 16 (1)

Background CCND1 copy number increase is characteristic of acral melanoma and is useful in distinguishing benign and malignant acral melanocytic lesio......

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