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Metformin alleviates cisplatin-induced ototoxicity by autophagy induction possibly via the AMPK/FOXO3a pathway

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (4)

Cisplatin is an antitumor drug that is widely used for the treatment of various solid tumors. Unfortunately, patients are often troubled by serious si......

Clinical significance of mismatch negativity in predicting the awakening of comatose patients after severe brain injury

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 126 (1)

We assessed the clinical significance of mismatch negativity (MMN) in predicting the awakening of comatose patients with severe brain injury. The clin......

Sensorimotor knowledge from task-irrelevant feedback contributes to motor learning

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 126 (1)

Exposure to task-irrelevant feedback leads to perceptual learning, but its effect on motor learning has been understudied. Here, we asked human partic......

Approaches to revealing the neural basis of muscle synergies: a review and a critique

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (5)

The central nervous system (CNS) may produce coordinated motor outputs via the combination of motor modules representable as muscle synergies. Identif......

Involvement of the BNP/NPR-A/BKCa pathway in rat trigeminal ganglia following chronic constriction injury

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (4)

Accumulating evidence indicates that the brain natriuretic peptide (BNP) and its receptor (natriuretic peptide receptor, NPR) are widely distributed i......

Differential contributions of voltage-gated potassium channel subunits in enhancing temporal coding in the bushy cells of the ventral cochlear nucleus

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (5)

Temporal coding precision of bushy cells in the ventral cochlear nucleus (VCN), critical for sound localization and communication, depends on the gene......

The duration of withdrawal affects the muscarinic signaling in the nucleus accumbens after chronic morphine exposure in neonatal rats

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (6)

The infants experience withdrawal from opiates, and time-dependent adaptations in neuronal activity of nucleus accumbens (NAc) may be crucial for this......

Transcranial direct current stimulation relieves visceral hypersensitivity via normalizing GluN2B expression and neural activity in anterior cingulate cortex

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (5)

Irritable bowel syndrome (IBS) is one of the most common challenging diseases for clinical treatment. The aim of this study is to investigate whether ......

Exogenous insulin-like growth factor 1 attenuates sevoflurane anesthesia-induced cognitive dysfunction in aged rats

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (6)

Sevoflurane anesthesia is correlated with the generation of postoperative cognitive dysfunction. Insulin-like growth factor 1 (IGF-1) has important fu......

A model of metabolic supply-demand mismatch leading to secondary brain injury

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 126 (2)

Secondary brain injury (SBI) is defined as new or worsening injury to the brain after an initial neurologic insult, such as hemorrhage, trauma, ischem......

Activation of oxytocin receptor in the trigeminal ganglion attenuates orofacial ectopic pain attributed to inferior alveolar nerve injury

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2021; 125 (1)

This study explores the effects of oxytocin receptor (OXTR) in the trigeminal ganglion (TG) on orofacial neuropathic pain. We demonstrate that OXTR ac......

Sequential activation of multiple persistent inward currents induces staircase currents in serotonergic neurons of medulla in ePet-EYFP mice

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2020; 123 (1)

Persistent inward currents (PICs) are widely reported in rodent spinal neurons. A distinctive pattern observed recently is staircase-like PICs induced......

Disparity in interaural time difference improves the accuracy of neural representations of individual concurrent narrowband sounds in rat inferior colliculus and auditory cortex

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2020; 123 (2)

The central mechanisms underlying binaural unmasking for spectrally overlapping concurrent sounds, which are unresolved in the peripheral auditory sys......

Savings in sensorimotor adaptation without an explicit strategy

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2020; 123 (3)

The hallmark of long-term retention of sensorimotor adaptation is a faster relearning when similar perturbations are encountered again. However, what ......

Divisive gain modulation enables flexible and rapid entrainment in a neocortical microcircuit model

期刊: JOURNAL OF NEUROPHYSIOLOGY, 2020; 123 (3)

Neocortical circuits exhibit a rich dynamic repertoire, and their ability to achieve entrainment (adjustment of their frequency to match the input fre......

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