期刊： LABORATORY INVESTIGATION, 2021; 101 (7)
Rett syndrome (RTT) is a rare neurodevelopmental disorder that results in severe multiple disabilities. This study provides evidence that exosomal miR......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Asthma is an allergic inflammatory lung disease affecting nearly 300 million people worldwide. To better understand asthma, new regulators must be ide......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
overexpression of the microRNA miR-182 promotes functional recovery and reduced histopathological changes in spinal cord injury mice. miR-182 overexpr......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Epithelial-mesenchymal transition (EMT) plays a crucial role in the development of pulmonary fibrosis. This study aims to investigate the effects of v......
期刊： LABORATORY INVESTIGATION, 2021; 101 (10)
The authors aimed to provide new insights into the pathogenesis and treatment of cutaneous burns. They show that the plant polyphenol resveratrol cont......
期刊： LABORATORY INVESTIGATION, 2021; 101 (10)
Synovial hyperplasia, a profound alteration in the structure of synovial tissue, is the basis for cumulative joint destruction in rheumatoid arthritis......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Hyperglycemia is a pivotal driver of vascular complications in diabetes. The present study shows that the long non-coding RNA SNHG15 is downregulated ......
期刊： LABORATORY INVESTIGATION, 2021; 101 (10)
Sepsis is an acute inflammatory reaction and a cause of acute respiratory distress syndrome (ARDS). In the present study, we explored the roles and un......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
This paper demonstrates that PHLDA3 is highly expressed in lung adenocarcinomas and correlates with poor outcome. PHLDA3, in conjunction with GSK3 bet......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Uremic toxin accumulation is one possible reason for alterations in hepatic drug metabolism in patients with chronic kidney disease (CKD). However, th......
期刊： LABORATORY INVESTIGATION, 2021; 101 (10)
The authors show that curcumin suppresses the proliferation and migration of acute myeloid leukemia (AML) cells. Curcumin also blocks cell cycle progr......
期刊： LABORATORY INVESTIGATION, 2021; 101 (7)
M2 microglia-derived EVs inhibit neuronal autophagic activity. Mechanistically, M2 microglia-derived EVs deliver miR-135a-5p into neuronal cells to in......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide. Macrophages exhibit different functional states and are classified ......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Long non-coding RNAs (lncRNAs) have been found to play regulatory roles in cancers; for example, UCC was reported to promote colorectal cancer progres......
期刊： LABORATORY INVESTIGATION, 2021; 101 (9)
Retinal ganglion cell (RGC) death occurs after optic nerve injury due to acute trauma or chronic degenerative conditions such as optic neuropathies (e......
