期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Pharmacological blockade of the cannabinoid type 1 receptor, a G protein-coupled receptor expressed in the central nervous system and various peripher......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Plasma LDL is produced from catabolism of VLDL and cleared from circulation mainly via the hepatic LDL receptor (LDLR). Proprotein convertase subtilis......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Carotid atherosclerosis is a risk factor for ischemic stroke, one of the main causes of mortality and disability worldwide. The disease is characteriz......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Cholesterol is an essential component of the mammalian plasma membrane involved in diverse cellular processes. Our recent quantitative imaging analysi......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Genetic variants that increase the risk of fatty liver disease and cirrhosis have recently been identified in the proximity of membrane-bound O-acyltr......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
The pleiotropic actions of adiponectin in improving cell survival and metabolism have motivated the development of small-molecule therapeutic agents f......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Vascular disease contributes to neurodegeneration, which is associated with decreased blood pressure in older humans. Plasmalogens, ether phospholipid......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
The oxysterol sulfate, 25-hydroxy cholesterol 3-sulfate (25HC3S), has been shown to play an important role in lipid metabolism, inflammatory response,......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Endothelial-to-mesenchymal transition (EndMT), the process by which an endothelial cell (EC) undergoes a series of molecular events that result in a m......
期刊: JOURNAL OF LIPID RESEARCH, 2021; 62 ()
Cytosolic sulfotransferases (SULTs) catalyze the transfer of a sulfonate group from the cofactor 3'-phosphoadenosine 5'-phosphosulfate to a hydroxyl (......
期刊: JOURNAL OF LIPID RESEARCH, 2020; 61 (5)
Adipocytes take up long chain FAs through diffusion and protein-mediated transport, whereas FA efflux is considered to occur by diffusion. To identify......
期刊: JOURNAL OF LIPID RESEARCH, 2020; 61 (7)
The glycerol phosphate pathway produces more than 90% of the liver triacylglycerol (TAG). LysoPA, an intermediate in this pathway, is produced by glyc......
期刊: JOURNAL OF LIPID RESEARCH, 2020; 61 (7)
Excessive lipid deposition is a hallmark of NAFLD. Although much has been learned about the enzymes and metabolites involved in NAFLD, few studies hav......
期刊: JOURNAL OF LIPID RESEARCH, 2020; 61 (7)
Multi-component lipid emulsions, rather than soy-oil emulsions, prevent cholestasis by an unknown mechanism. Here, we quantified liver function, bile ......