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Immunologic Testing for SARS-CoV-2 Infection from the Antigen Perspective

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (5)

Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally......

Clinical and Analytical Evaluation of the Alinity m HR HPV Assay within the VALGENT-3 Framework

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (6)

Only clinically validated human papillomavirus (HPV) tests should be used in cervical cancer screening. VALGENT provides a framework to validate new H......

Development of an Indirect Chemiluminescence Immunoassay Using a Multiepitope Recombinant Protein To Specifically Detect Antibodies against Foot-and-Mouth Disease Virus Serotype O in Swine

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (3)

Foot-and-mouth disease virus (FMDV) has led to serious losses in animal husbandry worldwide. Seromonitoring of FMDV postvaccination is important for t......

Development of a Subtyping Tool for Zoonotic Pathogen Cryptosporidium canis

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (3)

Cryptosporidium canis is an important cause of cryptosporidiosis in canines and humans. Studies of the transmission characteristics of C. canis are cu......

Deep Neural Networks Offer Morphologic Classification and Diagnosis of Bacterial Vaginosis

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Bacterial vaginosis (BV) is caused by the excessive and imbalanced growth of bacteria in vagina, affecting 30 to 50% of women. Gram staining followed ......

Evaluation of a SARS-CoV-2 Surrogate Virus Neutralization Test for Detection of Antibody in Human, Canine, Cat, and Hamster Sera

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Surrogate neutralization assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can be done without biosafety level 3 containmen......

Dynamics of Hepatitis E Virus (HEV) Antibodies and Development of a Multifactorial Model To Improve the Diagnosis of HEV Infection in Resource-Limited Settings

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Serological markers are important for the diagnosis of hepatitis E virus (HEV) infection. This study aims to compare the diagnostic performance of the......

Evaluation of Molecular Serotyping Assays for Shigella flexneri Directly on Stool Samples

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Shigella flexneri is prevalent worldwide and is the most common Shigella species in many countries. At least 19 S. flexneri serotypes exist, and serot......

GenSeizer: a Multiplex PCR-Based Targeted Gene Sequencing Platform for Rapid and Accurate Identification of Major Mycobacterium Species

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Mycobacterium tuberculosis and nontuberculous mycobacterium (NTM) infections often exhibit similar clinical symptoms. Timely and effective treatment r......

Serum-Based Diagnosis of Pediatric Tuberculosis by Assay of Mycobacterium tuberculosis Factors: a Retrospective Cohort Study

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen c......

Novel Method for Isolation of Porcine Epidemic Diarrhea Virus with the Use of Suspension Vero Cells and Immunogenicity Analysis

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (2)

In February and December of 2019, two large-scale outbreaks of diarrhea were observed in the same swine farm with 3,000 sows in Shanghai, China. We su......

Value of Xpert MTB/RIF Using Bronchoalveolar Lavage Fluid for the Diagnosis of Pulmonary Tuberculosis: a Systematic Review and Meta-analysis

期刊: JOURNAL OF CLINICAL MICROBIOLOGY, 2021; 59 (4)

The performance of Xpert MTB/RIF using bronchoalveolar lavage fluid (BAL) for the diagnosis of pulmonary tuberculosis (PTB) remains unclear. Therefore......

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