期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (9)
Background After binding to their corresponding receptors, cytokines mediate a variety of biological activities. However, the activity of cytokines in......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (11)
In lung adenocarcinoma (LUAD), the appearance of morphologically diverse tumor regions, termed histological patterns, is closely associated with disea......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (2)
Introduction: Chemotherapy and radiotherapy have been reported to be basically ineffective for pancreatic ductal adenocarcinoma patients; thus, gene t......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (2)
Background Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Recent studies have demonstrated that lncRNAs play an important......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (7)
Background In China, most esophageal cancer patients are squamous cell carcinomas and are treated with taxane-containing regimens; however, few studie......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (1)
Background Circular RNA itchy E3 ubiquitin protein ligase (circ-ITCH) has previously been reported to play a key role in carcinogenesis. Nevertheless,......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (1)
Background Hypertrophic cardiomyopathy (HCM) is a hereditary disease manifested by a thickened ventricular wall. Cysteine and glycine-rich protein 3 (......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (3)
Background This study was designed to verify whether enhancer of zeste homolog 2 (EZH2) affects intervertebral disc degeneration (IVDD) development th......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (5)
Background: Inadequate trophoblast invasion is associated with preeclampsia (PE). Ankyrin repeat domain protein 37 (ANKRD37) has been reported to be a......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (10)
Background The Notch signaling pathway is involved in the progression of esophageal squamous cell carcinoma (ESCC), although the roles of single nucle......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (10)
Objectives The molecular mechanistic actions of tumor-derived extracellular vesicles (EVs) in modulating macrophage polarization in the tumor microenv......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (9)
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and advanced interstitial lung disease with poor prognosis. AHNAK nucleoprotein 2 (AHNAK2......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (3)
Background Noninvasive prenatal testing (NIPT) for common fetal aneuploidies has been widely adopted in clinical practice for its sensitivity and accu......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (8)
Background Synaptogyrin-2 (SYNGR2) plays an important role in regulating membrane traffic in non-neuronal cells. However, the role of SYNGR2 in esopha......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (4)
Background Accumulating evidence suggests that several microRNA (miRNA) polymorphisms are closely associated with disease susceptibility or progressio......