期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 222 ()
alpha-Conotoxins are disulfide-rich and well-structured peptides, most of which can block nicotinic acetylcholine receptors (nAChRs) with exquisite se......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 226 ()
Increasing evidence indicates that dysfunction of glutamate receptors is involved in the pathophysiology of major depressive disorder (MDD). Although ......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 226 ()
Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly caused by shortages of effective medical intervention and p......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 225 ()
Chronic pain remains an enormous health problem affecting approximatively 30% of the world's population. Opi-oids as the first line analgesics often l......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 226 ()
Pancreatic cancer is one of the malignant tumors with poor prognosis. The molecular mechanisms of pancreatic oncogenesis and malignant progression are......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 224 ()
Traditional Chinese medicines (TCMs) produce chemically diverse functional compounds that are importantly chemical resource for facilitating new drug ......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 224 ()
Metabolic reprogramming is a hallmark of cancer and increasing evidence suggests that reprogrammed cell metabolism supports tumor initiation, progress......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 226 ()
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is characterized by persistent inflammation in a hereditarily......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 222 ()
Targeted therapy is an emerging treatment strategy for alcoholic liver disease (ALD). Inflammation plays an important role in the occurrence and devel......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 226 ()
Adequate food intake and relative abundance of dietary nutrients have undisputed effects on the brain function. There is now substantial evidence that......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 223 ()
Cellular senescence constitutes a permanent state of cell cycle arrest in proliferative cells induced by different stresses. The exploration of tumor ......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 222 ()
Liver fibrosis is a dynamic wound-healing process associated with the deposition of extracellular matrix pro-duced by myofibroblasts. HSCs activation,......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 221 ()
Cardiocerebrovascular disease is a collective term for cardiovascular and cerebrovascular diseases. Because of the complex mechanisms involved in card......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 223 ()
Drug addiction is one of the leading causes of mortality worldwide. Despite great advances were achieved in un-derstanding the neurobiology of drug ad......
期刊： PHARMACOLOGY & THERAPEUTICS, 2021; 225 ()
Stroke constitutes the second leading cause of death and a major cause of disability worldwide. Stroke is normally classified as either ischemic or he......
