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Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2021; 82 ()

The simultaneous maturation of multiple digital and telecommunications technologies in 2020 has created an unprecedented opportunity for ophthalmology......

Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: Histology and clinical features

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2021; 83 ()

The optic nerve head can morphologically be differentiated into the optic disc with the lamina cribrosa as its basis, and the parapapillary region wit......

Aqueous outflow regulation-21st century concepts

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2021; 83 ()

We propose an integrated model of aqueous outflow control that employs a pump-conduit system in this article. Our model exploits accepted physiologic ......

Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2021; 80 ()

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are driven by auto inflammatory or autoimmune responses, such ......

Recapitulating developmental mechanisms for retinal regeneration

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2020; 76 ()

Degeneration of specific retinal neurons in diseases like glaucoma, age-related macular degeneration, and retinitis pigmentosa is the leading cause of......

Exploring choroidal angioarchitecture in health and disease using choroidal vascularity index

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2020; 77 ()

The choroid is one of the most vascularized structures of the human body and plays an irreplaceable role in nourishing photoreceptors. As such, choroi......

The transcription factor MITF in RPE function and dysfunction

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2019; 73 ()

Dysfunction and loss of the retinal pigment epithelium (RPE) are hallmarks of retinal degenerative diseases in mammals. A critical transcription facto......

JIF:11.77

Stemming retinal regeneration with pluripotent stem cells

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2019; 69 ()

Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse diseases, such as age related macular degeneration (A......

JIF:11.77

The epidemics of myopia: Aetiology and prevention

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2018; 62 ()

There is an epidemic of myopia in East and Southeast Asia, with the prevalence of myopia in young adults around 80-90%, and an accompanying high preva......

JIF:11.77

Epigenetics, microbiota, and intraocular inflammation: New paradigms of immune regulation in the eye

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2018; 64 ()

Sight threatening immune responses that damage the eye characterize intraocular inflammatory diseases. These diseases including uveitis and age-relate......

JIF:11.77

Dopamine signaling and myopia development: What are the key challenges

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2017; 61 ( )

In the face of an "epidemic" increase in myopia over the last decades and myopia prevalence predicted to reach 2.5 billion people by the end of this d......

JIF:11.65

Imaging retina to study dementia and stroke

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2017; 57 ( )

With increase in life expectancy, the number of persons suffering from common age-related brain diseases, including neurodegenerative (e.g., dementia)......

JIF:11.65

Primary angle closure glaucoma: What we know and what we don't know

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2017; 57 ( )

Primary angle-closure glaucoma (PACG) is a common cause of blindness. Angle closure is a fundamental pathologic process in PAGC. With the development ......

JIF:11.65

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2022; 89 ()

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with several underlying pathophysiological mechanisms, some of which......

JIF:19.69

Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma

期刊: PROGRESS IN RETINAL AND EYE RESEARCH, 2022; 89 ()

Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death, are the most frequently observed primary intraocular malignancies i......

JIF:19.69

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