期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (8)
Background Although both the patterns and accumulation of multimorbidity are important for predicting physical function, studies have not simultaneous......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (9)
Background Emerging evidence showed that bone metabolism and cardiovascular disease (CVD) are closely related. We previously observed a potential imme......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (3)
Nitric oxide (NO)-mediated vasodilatation is a fundamental response of vasculature, however, regulation of NO signaling pathway on resistance vessels ......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (3)
Background: With the dramatically rapid rate of aging worldwide, the maintenance of cognitive function in old age is a major public health priority. T......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (5)
Background Exposure to air pollution is associated with several chronic diseases and subclinical processes that could subsequently contribute to physi......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (5)
Growth differentiation factor 11 (GDF11), also known as bone morphogenetic protein 11, has been shown to have rejuvenation and antiaging properties, b......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (11)
Background Despite the growing evidence on the relationship between community environment and depressive symptoms, little is known about the longitudi......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (11)
Senescent cells express and secrete a variety of extracellular modulators that include cytokines, chemokines, proteases, growth factors, and some enzy......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (3)
Background: Preoperative administration of methylprednisolone reduced circulating markers of endothelial activation. This randomized, double-blind, pl......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (11)
Background Klemera-Doubal's method (KDM) is an advanced and widely applied algorithm for estimating biological age (BA), but it has no uniform paradig......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (1)
Background: Evidence regarding the associations of tooth loss and denture use with incident cognitive impairment is inconclusive in older adults, and ......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (11)
Nutrition intervention has emerged as a potential strategy to delay aging and promote healthy longevity. Citri Reticulatae Semen (CRS) has diverse ben......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (2)
Women with premature ovarian insufficiency (POI) may be more vulnerable to a variety of health risks. To seek a new method to treat the disease, the e......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (8)
AMP-activated protein kinase (AMPK) is involved in life-span maintenance, stress responses, and germ cell cycle arrest upon dauer entry. AMPK is curre......
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022; 77 (10)
Calorie restriction (CR) without malnutrition increases the health and life span of diverse taxa. The mechanism(s) behind CR are debated but may be di......