期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (4)
Author summary Worldwide, ecosystems are collapsing or in danger of collapse, but the precise causes of these collapses are often unknown. Observation......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (5)
Author summary In the past decade advances in computing and single cell sequencing technologies have ushered in a new era of discovery in biology and ......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (4)
The binding affinities of protein-nucleic acid interactions could be altered due to missense mutations occurring in DNA- or RNA-binding proteins, ther......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (5)
Sequence-based residue contact prediction plays a crucial role in protein structure reconstruction. In recent years, the combination of evolutionary c......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (7)
miRNAs belong to small non-coding RNAs that are related to a number of complicated biological processes. Considerable studies have suggested that miRN......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (7)
Author summary Gap junctions, or sites of direct electrical connections between neurons, have a significant presence in the cortex, both during develo......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (3)
Atherosclerotic plaque rupture is responsible for a majority of acute vascular syndromes and this study aims to develop a prediction tool for plaque p......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (7)
Biomechanical forces intimately contribute to cardiac morphogenesis. However, volumetric imaging to investigate the cardiac mechanics with high tempor......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (8)
Effective and powerful survival mediation models are currently lacking. To partly fill such knowledge gap, we particularly focus on the mediation anal......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (3)
Author summary The dominant view of perceptual confidence proposes that confidence optimally reflects the probability that a decision is correct. But ......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (5)
Author summary TBM (template-based modeling) is a popular method for protein structure prediction. However, existing methods cannot generate good mode......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (8)
Retinotopic mapping, i.e., the mapping between visual inputs on the retina and neuronal activations in cortical visual areas, is one of the central to......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (8)
Author summary Cancer is one of the most heterogeneous diseases, characterized by diverse morphological, phenotypic, and genomic profiles between tumo......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (5)
Animals utilize a variety of active sensing mechanisms to perceive the world around them. Echolocating bats are an excellent model for the study of ac......
期刊: PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (6)
Synchronous oscillations in neural populations are considered being controlled by inhibitory neurons. In the granular layer of the cerebellum, two maj......