期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Central sensitization is considered a critical pathogenic mechanism of chronic migraine (CM). Activation of microglia in the trigeminal nuc......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
BackgroundMigraine constitutes a global health burden, and its pathophysiology is not well-understood; research evaluating cerebral perfusion and alte......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Neurovascular contact (NVC) is the main cause of primary trigeminal neuralgia (PTN); however, cases of PTN without NVC are still observed. ......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Granger causality analysis (GCA) has been used to investigate the pathophysiology of migraine. Amygdala plays a key role in pain modulation......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Medication-overuse headache (MOH) is a relatively frequently occurring secondary headache caused by overuse of analgesics and/or acute migr......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Central sensitization is one of the characters of chronic migraine (CM). Aberrant synaptic plasticity can induce central sensitization. Oxy......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Mutations in ATP1A2, the gene encoding the alpha 2 subunit of Na+/K+-ATPase, are the main cause of familial hemiplegic migraine type 2 (FHM......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Purpose Migraine is often accompanied with chronic tinnitus that will affect the cerebral blood flow (CBF) and exacerbate the tinnitus distress. Howev......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Novel neuroimaging strategies have the potential to offer new insights into the mechanistic basis for trigeminal neuralgia (TN). The presen......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background Cluster headache (CH) is a trigeminal autonomic cephalalgia (TAC) characterized by a highly disabling headache that negatively impacts qual......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
In countries where headache services exist at all, their focus is usually on specialist (tertiary) care. This is clinically and economically inappropr......
期刊: JOURNAL OF HEADACHE AND PAIN, 2021; 22 (1)
Background: Migraine is one of the most common neurological diseases around the world and calcitonin gene-related peptide (CGRP) plays an important ro......
期刊: JOURNAL OF HEADACHE AND PAIN, 2020; 21 (1)
Background: A previous study by our team reported the prevalence of primary headache disorders and factors associated with headache among nurses in th......
期刊: JOURNAL OF HEADACHE AND PAIN, 2020; 21 (1)
Background: According to our previous study, microglia P2X4 receptors (P2X4Rs) play a pivotal role in the central sensitization of chronic migraine (C......
期刊: JOURNAL OF HEADACHE AND PAIN, 2020; 21 (1)
Objective Numerous genetic variants from meta-analyses of observational studies and GWAS were reported to be associated with migraine susceptibility. ......