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Diagnostics, therapeutics and RET inhibitor resistance for RET fusion?positive non-small cell lung cancers and future perspectives

期刊: CANCER TREATMENT REVIEWS, 2021; 96 ()

Selective RET inhibitors is the current hot topic, making multikinase inhibitors a thing of the past. However, the limitation of various test approach......

Capmatinib for patients with non-small cell lung cancer with MET exon 14 skipping mutations: A review of preclinical and clinical studies

期刊: CANCER TREATMENT REVIEWS, 2021; 95 ()

The mesenchymal-epithelial transition (MET) receptor tyrosine kinase binds the hepatocyte growth factor to activate downstream cell signaling pathways......

Comparison of radiological criteria for hyperprogressive disease in response to immunotherapy

期刊: CANCER TREATMENT REVIEWS, 2020; 91 ()

Hyperprogressive disease (HPD) is a concerning paradoxical acceleration of cancer growth induced by immune drugs. The lack of standard radiological cr......

The landscape of new drugs in extranodal NK/T-cell lymphoma

期刊: CANCER TREATMENT REVIEWS, 2020; 89 ()

To date, much progress has been made in early-stage extranodal NK/T-cell lymphoma (ENKTCL), and risk-adapted therapy with radiotherapy (RT) alone for ......

Current management of stage IV nasopharyngeal carcinoma without distant metastasis

期刊: CANCER TREATMENT REVIEWS, 2020; 85 ()

Up to one in four patients with nasopharyngeal carcinoma present with non-metastatic stage IV disease (i.e. T4 or N3). Distinct failure patterns exist......

Imaging and clinical correlates with regorafenib in metastatic colorectal cancer

期刊: CANCER TREATMENT REVIEWS, 2020; 86 ()

In colorectal cancer (CRC), imaging is important in determining tumor stage, selecting treatment strategies, and in assessing response to therapy. How......

Special subtypes with favorable prognosis in breast cancer: A registry-based cohort study and network meta-analysis

期刊: CANCER TREATMENT REVIEWS, 2020; 91 ()

Background: We aimed to explore whether cribriform and adenoid cystic carcinoma had comparable prognoses to mucinous, tubular and papillary carcinoma,......

Interventional therapy combined with immune checkpoint inhibitors: Emerging opportunities for cancer treatment in the era of immunotherapy

期刊: CANCER TREATMENT REVIEWS, 2019; 74 ()

Immune checkpoint inhibitors-based immunotherapy offers a new effective modality in the treatment of advanced malignancies. Considering the remarkable......

JIF:8.33

Short-duration versus 1-year adjuvant trastuzumab in early HER2 positive breast cancer: A meta-analysis of randomized controlled trials

期刊: CANCER TREATMENT REVIEWS, 2019; 75 ()

Background: One year of adjuvant trastuzumab treatment is the standard of care for early stage human epidermal growth factor receptor 2 (HER2)-positiv......

JIF:8.33

Trametinib in the treatment of multiple malignancies harboring MEK1 mutations

期刊: CANCER TREATMENT REVIEWS, 2019; 81 ()

The aberrant activation of RAS-derived mitogen-activated protein kinase (MAPK) signaling pathway plays a prominent role in tumorigenesis of an array o......

JIF:8.33

Management of locally recurrent nasopharyngeal carcinoma

期刊: CANCER TREATMENT REVIEWS, 2019; 79 ()

As a consequence of the current excellent loco-regional control rates attained using the generally accepted treatment paradigms involving intensity-mo......

JIF:8.33

EGFR-directed monoclonal antibodies in combination with chemotherapy for treatment of non-small-cell lung cancer: an updated review of clinical trials and new perspectives in biomarkers analysis

期刊: CANCER TREATMENT REVIEWS, 2019; 72 ()

Lung cancer still represents one of the most common and fatal neoplasm, accounting for nearly 30% of all cancer-related deaths. Targeted therapies bas......

JIF:8.33

The promise of combining cancer vaccine and checkpoint blockade for treating HPV-related cancer

期刊: CANCER TREATMENT REVIEWS, 2019; 78 ()

Human papillomavirus (HPV)-associated intraepithelial neoplasia or cancers are ideal candidates for cancer immunotherapy since HPV oncoproteins, such ......

JIF:8.33

Quality assessment of cancer cachexia clinical practice guidelines

期刊: CANCER TREATMENT REVIEWS, 2018; 70 ()

Objectives: The aim of this study was to investigate the quality of clinical practice guidelines of cancer cachexia and identify gaps limiting knowled......

JIF:8.33

Advances in sarcoma gene mutations and therapeutic targets

期刊: CANCER TREATMENT REVIEWS, 2018; 62 ()

Sarcomas are rare and complex malignancies that have been associated with a poor prognostic outcome. Over the last few decades, traditional treatment ......

JIF:8.33

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