期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Posttranslational modification (PTM) and regulation of protein stability are crucial to various biological processes. Histone deacetylase 6 (HDAC6), a......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Recently, the role of several microRNAs (miRNAs or miRs) in pulmonary diseases has been described. The molecular mechanisms by which miR-21......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is characterized by the accumulation of immune cells and lipids......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Circular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), have a covalently closed circular structure resulting from pre-mRNA back splicing ......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Objectives Targeted inhibition of inflammatory response can reduce diabetic cerebral ischemia-reperfusion (I/R) injure. Pyroptosis is characterized by......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background The number of patients with diabetes is increasing worldwide. Diabetic testicular damage can cause spermiogenesis disorders and sexual dysf......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background It is known that increased gastrin concentration is negatively correlated with cardiovascular mortality, and plasma gastrin levels are incr......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background: Propofol, an intravenous anesthetic, was proven to protect against lung ischemia/reperfusion (I/R) injury. However, the detailed mechanism......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Intervertebral disc degeneration (IVDD) is the breakdown of the discs supporting the vertebrae. It is one of the most frequent causes of ba......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Neovasculogenesis is characteristic of herniated lumbar discs, in which extruded nucleus pulposus is prone to heme iron-induced cytotoxicit......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Oxidative stress is an important factor involved in the progress of heart failure. The current study was performed to investigate whether p......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
BackgroundExtracellular vesicles (EVs) derived from tumor cells are implicated in the progression of malignancies through the transfer of molecular ca......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Renin-angiotensin-aldosterone system activation is the critical factor in renal remodeling and dysfunction. Our previous study suggested th......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Increasing evidence has indicated that circular RNAs (circRNAs) play a role in various diseases. However, the influence of circRNAs in neph......
期刊: MOLECULAR MEDICINE, 2021; 27 (1)
Background Tongue squamous cell carcinoma (TSCC) ranks as the most prevalent malignancy in the oral cavity. TSCC patients with occult lymph node metas......