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Supplementation with high-dose cholecalciferol throughout pregnancy induces fetal growth restriction through inhibiting placental proliferation and trophoblast epithelial-mesenchymal transition

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 91 ()

Vitamin D deficiency has been associated with adverse pregnant outcomes. Several studies investigated the effects of maternal vitamin D3 supplementati......

Lycopene increases the proportion of slow-twitch muscle fiber by AMPK signaling to improve muscle anti-fatigue ability

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 94 ()

Lycopene has a wide range of biological functions, especially its antioxidant capacity. However, effects of lycopene on muscle fatigue resistant and m......

Toll-like receptor 3 ablation prevente d high-fat diet-induced obesity and metabolic disorder

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 95 ()

Inflammation in insulin-sensitive tissues (e.g., liver, visceral adipose tissue [VAT]) plays a major role in obesity and insulin resistance. Recruitme......

Saskatoon berry powder reduces hepatic steatosis and insulin resistance in high fat-high sucrose diet-induced obese mice

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 95 ()

Non-alcoholic fatty liver disease is a common metabolic disorder associated with insulin resistance and lacks a specific treatment. Our previous studi......

n-3 PUFAs protect against adiposity and fatty liver by promoting browning in postnatally overfed male rats: a role for NRG4

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 93 ()

Early-life nutrition plays an important role in regulating adult metabolism. This study evaluated the effects of early nutrition during the suckling a......

Calcium supplementation relieves high-fat diet-induced liver steatosis by reducing energy metabolism and promoting lipolysis

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 94 ()

Nonalcoholic fatty liver disease (NAFLD) is a chronic disease affecting the health of many people worldwide. Previous studies have shown that dietary ......

Adipocyte inducible 6-phosphofructo-2-kinase suppresses adipose tissue inflammation and promotes macrophage anti-inflammatory activation

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 95 ()

Obesity-associated inflammation in white adipose tissue (WAT) is a causal factor of systemic insulin resistance. To better understand how adipocytes r......

Anthocyanin-containing purple potatoes ameliorate DSS-induced colitis in mice

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 93 ()

Ulcerative colitis (UC), a major form of inflammatory bowel disease (IBD), is on the rise worldwide. Approximately three million people suffer from IB......

Natural products and skeletal muscle health

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 93 ()

Skeletal muscle (SkM) is essential for body movement, energy metabolism, and material metabolism, and directly influences the quality of human life. A......

Intermittent administration of a fasting-mimicking diet reduces intestinal inflammation and promotes repair to ameliorate inflammatory bowel disease in mice

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 96 ()

Recent studies have revealed that calorie restriction is able to modulate immune system and aid in intervention of immune disorders. Inflammatory bowe......

Ferulic acid exerts Nrf2-dependent protection against prenatal lead exposure-induced cognitive impairment in offspring mice

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 91 ()

Prenatal and/or early postnatal exposure to lead (Pb) may be associated with deficits in cognitive function in the toddler offspring, and oxidative st......

Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferrets

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 91 ()

Cigarette smoke (CS) is an independent risk factor in development of nonalcoholic steatohepatitis (NASH) and fibrosis. Lycopene, a carotenoid naturall......

High sucrose diet-induced dysbiosis of gut microbiota promotes fatty liver and hyperlipidemia in rats

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 93 ()

Excess sucrose intake has been found to be a major factor in the development of metabolic syndrome, especially in promoting nonalcoholic fatty liver d......

Caloric restriction following early-life high fat-diet feeding represses skeletal muscle TNF in male rats

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 91 ()

Chronic metabolic diseases are on the rise worldwide and their etiology is multifactorial. Among them, inflammatory components like Tumor Necrosis Fac......

Soyb ean-derive d gma-miR159a alleviates colon tumorigenesis by suppressing TCF7/MYC in mice

期刊: JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2021; 92 ()

Previous reports have shown that plant-derived microRNAs (miRNAs) regulate mammalian gene expression through dietary intake. Our prior study found tha......

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