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Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments

期刊: NATURE MICROBIOLOGY, 2021; 6 (8)

Chromatin immunoprecipitation followed by sequencing and RNA sequencing analyses reveal that the transcriptional activity of fungal conidia (spores) b......

A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase

期刊: NATURE MICROBIOLOGY, 2021; 6 (6)

The stalling global progress in the fight against malaria prompts the urgent need to develop new intervention strategies. Whilst engineered symbiotic ......

Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle

期刊: NATURE MICROBIOLOGY, 2021; 6 (6)

Most clonal lineages of Staphylococcus epidermidis are commensals present on human skin and in the nose. However, some globally spreading healthcare-a......

Fungal taxonomy and sequence-based nomenclature

期刊: NATURE MICROBIOLOGY, 2021; 6 (5)

The identification and proper naming of microfungi, in particular plant, animal and human pathogens, remains challenging. Molecular identification is ......

Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency

期刊: NATURE MICROBIOLOGY, 2021; 6 (5)

MicroRNA miR-138, which is highly expressed in neurons, represses herpes simplex virus 1 (HSV-1) lytic cycle genes by targeting viral ICP0 messenger R......

IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

The retinoic acid-inducible gene I (RIG-I) receptor senses cytoplasmic viral RNA and activates type I interferons (IFN-I) and downstream antiviral imm......

SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

A group convened and led by the Virus Evolution Working Group of the World Health Organization reports on its deliberations and announces a naming sch......

Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

Zoonotic arenaviruses can lead to life-threating diseases in humans. These viruses encode a large (L) polymerase that transcribes and replicates the v......

Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

High-fat diet decreases antibiotic efficacy in a mouse model via an altered gut microbiota and decreased indole-3-acetic acid, which potentially conve......

LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

The emergent fungal pathogen Candida auris exhibits high resistance to antifungal drugs and environmental stresses, impeding treatment and decontamina......

A standardized archaeal taxonomy for the Genome Taxonomy Database

期刊: NATURE MICROBIOLOGY, 2021; 6 (7)

The accrual of genomic data from both cultured and uncultured microorganisms provides new opportunities to develop systematic taxonomies based on evol......

The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response

期刊: NATURE MICROBIOLOGY, ; ()

The Salmonella Typhimurium effector protein SopD is capable of both activating and inhibiting the host inflammatory response by modulating Rab8 GTPase......

Trace gas oxidizers are widespread and active members of soil microbial communities

期刊: NATURE MICROBIOLOGY, 2021; 6 (2)

Soil microorganisms globally are thought to be sustained primarily by organic carbon sources. Certain bacteria also consume inorganic energy sources s......

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

期刊: NATURE MICROBIOLOGY, 2021; 6 (3)

The gut microbiome can influence the development of tumours and the efficacy of cancer therapeutics(1-5); however, the multi-omics characteristics of ......

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