期刊： SCIENCE SIGNALING, 2021; 14 (678)
The RIG-I-like receptor (RLR) signaling pathway is pivotal for innate immunity against invading viruses, and dysregulation of this molecular cascade h......
期刊： SCIENCE SIGNALING, 2021; 14 (700)
Bacterial type IV pili (T4P) contribute to virulence and can be rapidly extended and retracted to mediate twitching motility. T4P biogenesis, which is......
期刊： SCIENCE SIGNALING, 2021; 14 (677)
Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that regulate various aspects of central nervous system processing in normal......
期刊： SCIENCE SIGNALING, 2021; 14 (690)
Coronavirus disease 2019 (COVID-19) has poorer clinical outcomes in males than in females, and immune responses underlie these sex-related differences......
期刊： SCIENCE SIGNALING, 2021; 14 (665)
Cranial neural crest cells (CNCCs) are a population of multipotent stem cells that give rise to craniofacial bone and cartilage during development. Bo......
期刊： SCIENCE SIGNALING, 2021; 14 (669)
Heterotopic ossification (HO) is a common, potentially debilitating pathology that is instigated by inflammation caused by tissue damage or other insu......
期刊： SCIENCE SIGNALING, 2021; 14 (671)
Ribosome biogenesis in eukaryotes requires the coordinated production and assembly of 80 ribosomal proteins and four ribosomal RNAs (rRNAs), and its r......
期刊： SCIENCE SIGNALING, 2020; 13 (626)
Type I interferons (IFNs) are the first line of defense against viral infection. Using a mouse model of influenza A virus infection, we found that IFN......
期刊： SCIENCE SIGNALING, 2020; 13 (629)
ANO1 (TMEM16A) is a Ca2+-activated Cl- channel (CaCC) expressed in peripheral somatosensory neurons that are activated by painful (noxious) stimuli. T......
期刊： SCIENCE SIGNALING, 2020; 13 (633)
The suppression of bone formation is a hallmark of multiple myeloma. Myeloma cells inhibit osteoblastogenesis from mesenchymal stem cells (MSCs), whic......
期刊： SCIENCE SIGNALING, 2020; 13 (638)
N-methyl-D-aspartate (NMDA) glutamate receptors (NMDARs) containing GluN2B subunits are prevalent early after birth in most brain regions in rodents. ......
期刊： SCIENCE SIGNALING, 2020; 13 (638)
Chaperones in the endoplasmic reticulum (ER) control the flux of Ca2+ ions into mitochondria, thereby increasing or decreasing the energetic output of......
期刊： SCIENCE SIGNALING, 2020; 13 (640)
Plants defend against herbivores and nematodes by rapidly sending signals from the wounded sites to the whole plant. We investigated how plants genera......
期刊： SCIENCE SIGNALING, 2020; 13 (642)
Certain probiotics have beneficial effects on the function of the central nervous system through modulation of the gut-brain axis. Here, we describe a......
期刊： SCIENCE SIGNALING, 2020; 13 (643)
Two-component systems (TCSs), which consist of a histidine kinase (HK) sensor and a response regulator (RR), are important for bacteria to quickly sen......
