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Targeted delivery of edaravone by liposomes for the treatment of ischemic stroke

期刊: NANOMEDICINE, 2022; 17 (11)

Aim: To construct an edaravone-encapsulated liposomes (EDV-LIPs) formulation against acute ischemic stroke. Methods: EDV-LIPs were prepared by the fil......

JIF:4.282

Advancements in the studies of novel nanomaterials for inner ear drug delivery

期刊: NANOMEDICINE, 2022; 17 (20)

Hearing loss is currently one of the most prevalent sensory disorders worldwide. Because both the blood-labyrinth barrier and the limited blood circul......

JIF:4.282

A nano-phytochemical ophthalmic solution for marked improvement of corneal wound healing in healthy or diabetic mice

期刊: NANOMEDICINE, 2022; 17 (3)

Aim: To formulate a novel nano-phytochemical ophthalmic solution to promote corneal wound healing. Methods: Dipotassium glycyrrhizinate (DG) and palma......

JIF:4.282

Small extracellular vesicles from iPSC-derived mesenchymal stem cells ameliorate tendinopathy pain by inhibiting mast cell activation

期刊: NANOMEDICINE, 2022; 17 (8)

Aim: This study aimed to explore the effect of small extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells (iMSC-sE......

JIF:4.282

Preparation and evaluation of paclitaxel-loaded reactive oxygen species and glutathione redox-responsive poly(lactic-co-glycolic acid) nanoparticles for controlled release in tumor cells

期刊: NANOMEDICINE, 2022; 17 (22)

Aim: To formulate and assess the anticancer effect of the poly(lactic-co-glycolic acid) (PLGA) copolymer with the thioether groups (diethyl sulfide [D......

JIF:4.282

Celastrol-based nanomedicine hydrogels eliminate posterior capsule opacification

期刊: NANOMEDICINE, 2022; 17 (20)

Aim: To formulate an injectable thermosensitive micelle-hydrogel hybrid system loaded with celastrol (celastrol-loaded micelle hydrogel: CMG) to preve......

JIF:4.282

Nanoparticle albumin-bound paclitaxel is superior to liposomal paclitaxel in the neoadjuvant treatment of breast cancer

期刊: NANOMEDICINE, 2022; 17 (10)

Aim: The present study aimed to retrospectively compare the efficacy and safety between liposomal paclitaxel (Lps-P) and nanoparticle albumin-bound pa......

JIF:4.282

Polyglycerol fatty acid esters as alternatives to PEGylated lipids for liposome coating

期刊: NANOMEDICINE, 2022; 17 (14)

Background: Polyglycerol (PG) is a type of biocompatible hydrophilic polyether polyol, and it is considered as a potential alternative to polyethylene......

JIF:4.282

Synergistic chemo-photothermal and ferroptosis therapy of polydopamine nanoparticles for esophageal cancer

期刊: NANOMEDICINE, 2022; 17 (16)

Aim: To develop synergistic chemo-photothermal and ferroptosis therapy nanoparticles to improve the efficacy of treatment for esophageal cancer. Mater......

JIF:4.282

The effect of AS1411 surface density on the tumor targeting properties of PEGylated silver nanotriangles

期刊: NANOMEDICINE, 2022; 17 (5)

Aim: To determine the optimal AS1411 density on polyethylene glycol (PEG)ylated silver nanotriangles (PNTs) for targeting breast cancer cells. Methods......

JIF:4.282

Graphene oxide induces autophagy and apoptosis via ROS-dependent AMPK/mTOR/ULK-1 pathway in colorectal cancer cells

期刊: NANOMEDICINE, 2022; 17 (9)

Aim: To investigate the anticancer effects and action mechanism of graphene oxide (GO) in colorectal cancer (CRC). Materials & methods: Anticancer......

JIF:4.282

Detection of ATP in cancer cells with a label-free fluorescent aptasensor

期刊: NANOMEDICINE, 2022; 17 (11)

Aim: To develop a new detection technique for ATP in cancer cells using fluorescent biosensing. Materials & methods: This research presents a new ......

JIF:4.282

Potential of fluorescent nanoprobe in diagnosis and treatment of Alzheimer's disease

期刊: NANOMEDICINE, 2022; 17 (17)

Alzheimer's disease (AD) is well known for its insidious nature, slow progression and high incidence as a neurodegenerative disease. In the past, diag......

JIF:4.282

Targeted activation of HNF4 alpha/HGF1/FOXA2 reverses hepatic fibrosis via exosome-mediated delivery of CRISPR/dCas9-SAM system

期刊: NANOMEDICINE, 2022; 17 (20)

Aim: Hepatic fibrosis is one of the most common conditions worldwide, and yet no effective antifibrotic therapy is available. This study aimed to reve......

JIF:4.282

Recent advances in mesoporous silica nanoparticle-based targeted drug-delivery systems for cancer therapy

期刊: NANOMEDICINE, 2022; 17 (18)

Targeted drug-delivery systems are a growing research topic in tumor treatment. In recent years, mesoporous silica nanoparticles (MSNs) have been exte......

JIF:4.282

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