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More evidence for prediction model of radiosensitivity

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

With the development of precision medicine, searching for potential biomarkers plays a major role in personalized medicine. Therefore, how to predict ......

Genome-wide identification and characterization of perirenal adipose tissue microRNAs in rabbits fed a high-fat diet

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

MicroRNAs (miRNAs) are a class of endogenous single-stranded RNA molecules that play an important role in gene regulation in animals by pairing with t......

Long non-coding RNA LINC00488 facilitates thyroid cancer cell progression through miR-376a-3p/PON2

期刊: BIOSCIENCE REPORTS, 2021; 41 (3)

Objective: Long non-coding RNAs (lncRNAs) recently have been identified as influential indicators in a variety of malignancies. The aim of the present......

Lipidomic alteration of plasma in cured COVID-19 patients using ultra high-performance liquid chromatography with high-resolution mass spectrometry

期刊: BIOSCIENCE REPORTS, 2021; 41 (3)

Background: The pandemic of novel coronavirus disease 2019 (COVID-19) has become a serious public health crisis worldwide. The symptoms of COVID-19 va......

Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

Clear cell renal cell carcinoma (ccRCC) is the most common malignant type of kidney cancer. The present study aims to explore the underlying mechanism......

Validation of the functions and prognostic values of synapse-associated proteins in lower-grade glioma

期刊: BIOSCIENCE REPORTS, 2021; 41 (5)

Synapse and synapse-associated proteins (SAPs) play critical roles in various neurodegeneration diseases and brain tumors. However, in lower-grade gli......

The correlation between tumor-associated macrophage infiltration and progression in cervical carcinoma

期刊: BIOSCIENCE REPORTS, 2021; 41 (5)

Tumor microenvironment (TME) plays a particularly important role in the progression, invasion and metastasis of cervical carcinoma (CC). Tumor-associa......

Prediction of prognosis of patients with lung cancer in combination with the immune score

期刊: BIOSCIENCE REPORTS, 2021; 41 (5)

Purpose: The host's immune response to malignant tumor is fundamental to tumorigenesis and tumor development. The immune score is currently used to as......

Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma

期刊: BIOSCIENCE REPORTS, 2021; 41 (6)

N6-methyladenosine (m6A) methyltransferase has been shown to be an oncogene in a variety of cancers. Nevertheless, the relationship between the long n......

Identification of potential core genes and pathways predicting pathogenesis in head and neck squamous cell carcinoma

期刊: BIOSCIENCE REPORTS, 2021; 41 (5)

Head and neck squamous cell carcinoma (HNSCC) is the most common subtype of head and neck cancer; however, its pathogenesis and potential therapeutic ......

Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-alpha-cell axis

期刊: BIOSCIENCE REPORTS, 2021; 41 (6)

Glucagon plays an important role in glucose homeostasis and amino acid metabolism. It regulates plasma amino acid levels which in turn modulate glucag......

High expression of COL5A2, a member of COL5 family, indicates the poor survival and facilitates cell migration in gastric cancer

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

Background: Gastric cancer (GC) metastasis determines the prognosis of patients, and exploring the molecular mechanism of GC metastasis is expected to......

Resting metabolic rate and its adjustments as predictors of risk protein-energy wasting in hemodialysis patients

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

Background: The purpose of the present study was to explore the association between resting metabolic rate (RMR) and protein-energy wasting (PEW) risk......

Sublethal hyperthermia enhances anticancer activity of doxorubicin in chronically hypoxic HepG2 cells through ROS-dependent mechanism

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

Thermal ablation in combination with transarterial chemoembolization (TACE) has been reported to exert a more powerful antitumor effect than thermal a......

LncRNA AWPPH as a prognostic predictor in human cancers in Chinese population: evidence from meta-analysis

期刊: BIOSCIENCE REPORTS, 2021; 41 (4)

Background: Long non-coding RNA associated with poor prognosis of hepatocellular carcinoma (AWPPH) is dysregulated in a variety of human cancers. Howe......

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