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Association between the vertebrobasilar artery geometry and basilar artery plaques determined by high-resolution magnetic resonance imaging

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Atherosclerotic plaques are often present in regions of arteries with complicated flow patterns. Vascular morphology plays important role i......

Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Rodent brain slices-particularly hippocampal slices-are widely used in experimental investigations of epileptiform activity. Oxygenated art......

Sex effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson's disease

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Differences of genotypes between male and female have been studied in Parkinson's disease (PD), but limited research has focused on the com......

Docosahexaenoic fatty acid reduces the pro-inflammatory response induced by IL-1 beta in astrocytes through inhibition of NF-kappa B and AP-1 transcription factor activation

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflam......

Inhibitory control training reveals a common neurofunctional basis for generic executive functions and language switching in bilinguals

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background The neural networks underpinning language control and domain-general executive functions overlap in bilinguals, but existing evidence is ma......

Early postnatal irradiation-induced age-dependent changes in adult mouse brain: MRI based characterization

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Brain radiation exposure, in particular, radiotherapy, can induce cognitive impairment in patients, with significant effects persisting for......

Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Methamphetamine (METH) is one of the most widely abused illicit substances worldwide; unfortunately, its addiction mechanism remains unclea......

The disrupted topological properties of structural networks showed recovery in ischemic stroke patients: a longitudinal design study

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Introduction Stroke is one of the leading causes of substantial disability worldwide. Previous studies have shown brain functional and structural alte......

N/OFQ modulates orofacial pain induced by tooth movement through CGRP-dependent pathways

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Nociceptin/orphanin FQ (N/OFQ) has been revealed to play bidirectional roles in orofacial pain modulation. Calcitonin gene-related peptide ......

Impairments in brain perfusion, executive control network, topological characteristics, and neurocognition in adult patients with asymptomatic Moyamoya disease

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background: Asymptomatic Moyamoya disease (MMD) impairs hemodynamic and cognitive function. The relationship between these changes, cerebral blood flo......

Memantine ameliorates cognitive deficit in AD mice via enhancement of entorhinal-CA1 projection

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Memantine, a low- to moderate-affinity uncompetitive N-methyl-D-aspartate receptor antagonist, has been shown to improve cognitive function......

Brain multimodal co-alterations related to delay discounting: a multimodal MRI fusion analysis in persons with and without cocaine use disorder

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Delay discounting has been proposed as a behavioral marker of substance use disorders. Innovative analytic approaches that integrate inform......

Neural basis underlying the trait of attachment anxiety and avoidance revealed by the amplitude of low-frequency fluctuations and resting-state functional connectivity

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background Attachment theory demonstrates that early attachment experience shapes internal working models with mental representations of self and clos......

Eosinophil-to-monocyte ratio is a potential biomarker in the prediction of functional outcome among patients with acute ischemic stroke

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background It has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of......

Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice

期刊: BMC NEUROSCIENCE, 2021; 22 (1)

Background: Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cog......

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