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TMEM16F mediated phosphatidylserine exposure and microparticle release on erythrocyte contribute to hypercoagulable state in hyperuricemia

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2022; 96 ()

The link between hyperuricemia (HUA) and the risk of venous thromboembolism (VTE) has been well established. However, the mechanisms of thrombus gener......

JIF:2.453

Investigation on abnormal gene loci of a Chinese pedigree with hereditary combined deficiency of blood coagulation factor XI, XII, and protein S

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2022; 96 ()

Objective: In order to clarify the interaction mechanism, the phenotype and abnormal gene loci of FXI, FXII, and PS were investigated in this study. M......

JIF:2.453

Identification of TCR repertoires in asymptomatic COVID-19 patients by single-cell T-cell receptor sequencing

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2022; 97 ()

The T cell-mediated immune responses associated with asymptomatic infection (AS) of SARS-CoV-2 remain largely unknown. The diversity of T-cell recepto......

JIF:2.453

LXR beta is involved in the control of platelet production from megakaryocytes

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 89 ()

Liver X receptor beta (LXR beta), a nuclear receptor involved in important cellular processes such as cholesterol, glucose and fatty acid metabolism, ......

Good treatment-free survival of monoclonal gammopathy of undetermined significance associated pure red cell aplasia after bortezomib plus dexamethasone

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 89 ()

Pure red cell aplasia (PRCA) is a rare syndrome characterized by severe anemia and absence of erythroid precursors. PRCA associated to monoclonal gamm......

Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 86 ()

Introduction: Congenital fibrinogen disorders are characterized by heterogeneous clinical manifestations with mutations in the fibrinogen gene cluster......

Circ-PTK2 promotes the proliferation and suppressed the apoptosis of acute myeloid leukemia cells through targeting miR-330-5p/FOXM1 axis

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 86 ()

Background: Acute myeloid leukemia (AML) is characterized by malignant clonal disorder of blood cells with high relapse rate and low survival rate. Ci......

RNF220 promotes the proliferation of leukaemic cells and reduces the degradation of the Cyclin D1 protein through USP22

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 86 ()

Ring finger proteins contain a characteristic ring finger motif and perform a wide range of biological functions in living organisms. These genes are ......

MZF1 regulates alpha-globin gene transcription via long-range interactions in erythroid differentiation

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2021; 87 ()

Precise spatiotemporal gene expression regulation is crucial for human erythropoiesis. However, dramatic changes in the chromatin structure and transc......

Coagulopathy in cytogenetically and molecularly distinct acute leukemias at diagnosis: Comprehensive study

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2020; 81 ()

We analyzed the characteristics of coagulopathy in cytogenetically and molecularly distinct acute leukemias. We retrospectively analyzed 211 adult pat......

Down-regulation of lncRNA NEAT1 regulated by miR-194-5p/DNMT3A facilitates acute myeloid leukemia

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2020; 82 ()

Objective: miR-194-5p and NEAT1 have been reported to be associated with multiple malignancies, but their roles in acute myeloid leukemia (AML) remain......

Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells

期刊: BLOOD CELLS MOLECULES AND DISEASES, 2020; 84 ()

Eupalinilide E was assessed for ex-vivo expansion activity on hematopoietic stem cells (HSCs) from human cord blood (CB) CD34(+) cells in serum-free, ......

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