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SKA3 is a prognostic biomarker and associated with immune infiltration in bladder cancer

期刊: HEREDITAS, 2022; 159 (1)

Background Spindle and kinetochore-associated complex subunit 3 (SKA3) has recently been considered a key regulator of carcinogenesis. However, the co......

JIF:3.013

miR-31-5p from placental and peripheral blood exosomes is a potential biomarker to diagnose preeclampsia

期刊: HEREDITAS, 2022; 159 (1)

Background Preeclampsia, a multisystem disorder of unknown etiology, is one of the leading causes of maternal and perinatal morbidity and mortality. I......

JIF:3.013

Bioinformatics analysis of diagnostic biomarkers for Alzheimer's disease in peripheral blood based on sex differences and support vector machine algorithm

期刊: HEREDITAS, 2022; 159 (1)

Background The prevalence of Alzheimer's disease (AD) varies based on gender. Due to the lack of early stage biomarkers, most of them are diagnosed at......

JIF:3.013

Stages of preadipocyte differentiation: biomarkers and pathways for extracellular structural remodeling

期刊: HEREDITAS, 2022; 159 (1)

Background: This study utilized bioinformatics to analyze the underlying biological mechanisms involved in adipogenic differentiation, synthesis of th......

JIF:3.013

Integrative analyses of genes related to liver ischemia reperfusion injury

期刊: HEREDITAS, 2022; 159 (1)

Background Liver ischemia reperfusion injury (LIRI) is not only a common injury during liver transplantation and major hepatic surgery, but also one o......

JIF:3.013

Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation

期刊: HEREDITAS, 2022; 159 (1)

Background ATM (ataxia-telangiectasia mutated) protein kinase is highly conserved in metazoan, and plays a critical role at DNA damage response, oxida......

JIF:3.013

A novel molecular subtypes and risk model based on inflammatory response-related lncrnas for bladder cancer

期刊: HEREDITAS, 2022; 159 (1)

Background Inflammation and long noncoding RNAs (lncRNAs) are gradually becoming important in the development of bladder cancer (BC). Nevertheless, th......

JIF:3.013

Transcriptome sequencing reveals core regulation modules and gene signatures of Zusanli acupoints in response to different moxibustion warm stimulation in adjuvant arthritis rat

期刊: HEREDITAS, 2022; 159 (1)

Background The efficacy of moxibustion in treating rheumatoid arthritis is recognized, but its molecular mechanism is still unclear. This study aimed ......

JIF:3.013

Identification of four novel hub genes as monitoring biomarkers for colorectal cancer

期刊: HEREDITAS, 2022; 159 (1)

Background It must be admitted that the incidence of colorectal cancer (CRC) was on the rise all over the world, but the related treatment had not cau......

JIF:3.013

Identification of biomarkers, immune infiltration landscape, and treatment targets of ischemia-reperfusion acute kidney injury at an early stage by bioinformatics methods

期刊: HEREDITAS, 2022; 159 (1)

Background Mechanisms underlying ischemia/reperfusion injury-acute kidney injury (IRI-AKI) are not fully elucidated. We conducted an integrative analy......

JIF:3.013

Comprehensive analysis to identify pseudogenes/lncRNAs-hsa-miR-200b-3p-COL5A2 network as a prognostic biomarker in gastric cancer

期刊: HEREDITAS, 2022; 159 (1)

Objective Gastric cancer is one of the most common and deadly types of cancer. The molecular mechanism of gastric cancer progression remains unclear. ......

JIF:3.013

LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma

期刊: HEREDITAS, 2022; 159 (1)

Background Lysophosphatidic acid (LPA) and its receptors play a key role in regulating cancer progression. Upregulation of LPA receptor 2 (LPAR2) play......

JIF:3.013

Identification and development of the novel 7-genes diagnostic signature by integrating multi cohorts based on osteoarthritis

期刊: HEREDITAS, 2022; 159 (1)

Background: A chronic progressive degenerative joint disease, such as osteoarthritis (OA) is positively related to age. The medical economy is facing ......

JIF:3.013

SLC3A2 inhibits ferroptosis in laryngeal carcinoma via mTOR pathway

期刊: HEREDITAS, 2022; 159 (1)

Objective This study aimed to explore the mRNA and protein expression of SLC3A2 in laryngeal carcinoma cells and tissues, and functional regulatory me......

JIF:3.013

Association of novel MUC16, MAP3K15 and ABCA1 mutation with giant congenital melanocytic nevus

期刊: HEREDITAS, 2022; 159 (1)

Background Giant congenital melanocytic nevus (GCMN) is the benign nevomelanocytic proliferation. Mutations in NRAS have been previously detected in G......

JIF:3.013

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