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S100A8 accelerates wound healing by promoting adipose stem cell proliferation and suppressing inflammation

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Adipose-derived stem cells (ADSCs) are stem cells with multidirectional differentiation potential isolated from adipose tissue. They have the same imm......

Bone marrow mesenchymal stem cells alleviate the formation of pathological scars in rats

期刊: REGENERATIVE THERAPY, 2022; 20 ()

Introduction: Although bone marrow-derived mesenchymal stem cells (BMSCs) have attracted increasing attention because of their pivotal functions in th......

MiRNA-320a-5p contributes to the homeostasis of osteogenesis and adipogenesis in bone marrow mesenchymal stem cell

期刊: REGENERATIVE THERAPY, 2022; 20 ()

Objective: A number of miRNAs and their targets were dragged in the differentiation of bone marrow mesenchymal stem cells (BMSCs). We aimed to elabora......

Circ_0018168 inhibits the proliferation and osteogenic differentiation of fibroblasts in ankylosing spondylitis via regulating miR-330-3p/DKK1 axis

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Background: Circular RNAs (circRNAs) play a crucial regulatory role in human diseases. However, the roles of circRNAs in ankylosing spondylitis (AS) a......

Downregulated HDAC3 or up-regulated microRNA-296-5p alleviates diabetic retinopathy in a mouse model

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Objective: It has been demonstrated the efficacy of histone deacetylase 3 (HDAC3) in diabetes. Nevertheless, the function of HDAC3 in diabetic retinop......

Application of mesenchymal stem cells combined with nano-polypeptide hydrogel in tissue engineering blood vessel

期刊: REGENERATIVE THERAPY, 2022; 21 ()

At present, the vascular grafts used in clinic are mainly autologous blood vessels, but they often face the dilemma of no blood vessels available due ......

Downregulation of hsa_circ_0000885 suppressed osteosarcoma metastasis and progression via regulating E2F3 expression and sponging miR-16-5p

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Introduction: Accumulating evidence has shown that circular RNAs (circRNAs) have indispensable functions during tumor progression by regulating gene e......

Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Introduction: Numerous studies have shown that mesenchymal stem cells (MSCs) promote cutaneous wound healing via paracrine signaling. Our previous stu......

Circ_ROBO2/miR-186-5p/TRIM14 axis regulates oxidized low-density lipoprotein-induced cardiac microvascular endothelial cell injury

期刊: REGENERATIVE THERAPY, 2022; 20 ()

Background: Coronary artery disease (CAD) is one of the main risks of death, which is mainly caused by coronary arteries arteriosclerosis. Circular RN......

MiR-590-3p affects the function of adipose-derived stem cells (ADSCs) on the survival of skin flaps by targeting VEGFA

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Introduction: Partial necrosis of skin flaps is still a substantial problem in plastic and reconstructive surgery. In this study, the role of miR-590-......

Circ_0087960 stabilizes KDM5B by reducing SKP2 mediated ubiquitination degradation and promotes osteogenic differentiation in periodontal ligament stem cells

期刊: REGENERATIVE THERAPY, 2022; 19 ()

Background: Periodontitis is a common chronic oral disease among the world. Periodontal ligament stem cells (PDLSCs) has been proved to be a promising......

Therapeutic effects of asperosaponin VI in rabbit tendon disease

期刊: REGENERATIVE THERAPY, 2022; 20 ()

Introduction: This study explored the effects and molecular mechanisms of asperosaponin VI in tendon disease. Methods: Forty-eight purebred adult male......

miR-4739/ITGA10/PI3K signaling regulates differentiation and apoptosis of osteoblast

期刊: REGENERATIVE THERAPY, 2022; 21 ()

Introduction: To probe the impacts and biological roles of miR-4739/ITGA10 on the proliferation, differentiation and apoptosis of osteoblasts.Methods:......

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