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Pulmonary surfactant-associated protein B regulates prostaglandin-endoperoxide synthase-2 and inflammation in chronic obstructive pulmonary disease

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (5)

New Findings What is the central question of this study? It is reported that polymorphism of the gene for pulmonary surfactant-associated protein B (S......

Association of VEGFA polymorphisms with chronic obstructive pulmonary disease in Chinese Han and Mongolian populations

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (8)

New Findings What is the central question of this study? Vascular endothelial growth factor A (VEGFA) is an important growth factor involved in change......

LncRNA NEAT1 accelerates renal tubular epithelial cell damage by modulating mitophagy via miR-150-5p-DRP1 axis in diabetic nephropathy

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (7)

Diabetic nephropathy (DN) is a severe complication in diabetic patients, with a high mortality rate. Renal tubular injury is involved in the pathogene......

VE-cadherin N-glycosylation modified by N-acetylglucosaminyltransferase V regulates VE-cadherin-beta-catenin interaction and monocyte adhesion

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (9)

New Findings What is the central question of this study? Inflammation-induced monocyte adhesion is the initiator of most vascular diseases. The underl......

microRNA-22-3p plays a protective role in a murine asthma model through the inhibition of the NLRP3-caspase-1-IL-1 beta axis

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (8)

Asthma, a great public health burden, is triggered by inflammatory responses in the airways and these are not addressed appropriately by current thera......

Association between cortical thickness and distinct vascular cognitive impairment and dementia in patients with white matter lesions

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (7)

New Findings What is the central question of this study? White matter lesions (WMLs) are a brain disease characterized by altered brain structural and......

Leptin attenuates hypoxia-induced apoptosis in human periodontal ligament cells via the reactive oxygen species-hypoxia-inducible factor-1 alpha pathway

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (8)

Hypoxia-induced apoptosis of human periodontal ligament cells (hPDLCs) is an important contributor to the progression of various periodontal diseases.......

Fibrinogen-like protein 2 contributes to normal murine cardiomyocyte maturation and heart development

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (7)

New Findings What is the central question of this study? What is the role of fibrinogen-like protein 2 (FGL2) in murine cardiomyocyte maturation? What......

DBA/1 mice display equivalent cardiac function to C57BL/6J mice

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? Do normal adult DBA/1 mice have cardiac function and performance equal to those of C57BL/6J m......

Differential protein metabolism and regeneration in hypertrophic diaphragm and atrophic gastrocnemius muscles in hibernating Daurian ground squirrels

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? The aim was to investigate whether diaphragm hypertrophy and gastrocnemius atrophy during hib......

Role of miR-211 in a PC12 cell model of Alzheimer's disease via regulation of neurogenin 2

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? What is the mechanism of miR-211 in an Alzheimer's disease cell model? What is the main findi......

Endogenous production of n-3 polyunsaturated fatty acids protects mice from carbon tetrachloride-induced liver fibrosis by regulating mTOR and Bcl-2/Bax signalling pathways

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? What is the protective benefit of n-3 polyunsaturated fatty acids (PUFAs) on liver fibrosis a......

Gonadotrophin-releasing hormone receptor autoantibodies induce polycystic ovary syndrome-like features in a rat model

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? Is there a causal relationship between gonadotrophin-releasing hormone (GnRH) receptor-activa......

M-2 muscarinic autoantibodies and thyroid hormone promote susceptibility to atrial fibrillation and sinus tachycardia in an autoimmune rabbit model

期刊: EXPERIMENTAL PHYSIOLOGY, ; ()

New Findings What is the central question of this study? Do autoantibodies to the M-2 muscarinic receptor (M2R-AAbs) have the potential to facilitate ......

Danthron attenuates experimental atherosclerosis by targeting foam cell formation

期刊: EXPERIMENTAL PHYSIOLOGY, 2021; 106 (3)

New Findings What is the central question of this study? Does danthron alleviate experimental atherosclerosis by inhibiting the formation of foam cell......

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