Currently, vaccine is a promising tumor prevention modality in cancer therapy. However, it is hard to elicit robust antitumor immunity in patients alr......
Due to the homo-chirality preference of human body to most of chiral species, synthesizing enantiopure drugs and investigating the pharmacological act......
Innate immune cells, including natural killer cells and macrophages, are crucial in tumor surveillance and elimination. In contrast to the relatively ......
Most of tumor vaccines currently focus on inducing adaptive immunity, while the antitumor potential of innate immunity is getting more attentions. In ......
Phagocyte-mediated programmed cell removal (PrCR) plays an important role in the immunosurveillance and elimination of cancer cells. The induction of ......
Nanodevices have higher requirements for nanofabrication in tuning the size, shape and spatial arrangement of nanostructures and their assemblies in n......
Chemodynamic therapy (CDT) is a novel therapeutic modality that employs Fenton or Fenton-like reactions to destroy cancer cells via the disproportiona......
Massive bleeding and infectious complication remain the leading cause of worldwide trauma deaths. To tackle this issue, a platelet-inspired degradable......
Given the complexity, heterogeneity and metastasis of patient tumors, the combined therapy is usually applied in clinical applications. Internal radio......
Chemotherapy by certain types of anticancer drugs (e.g., doxorubicin (DOX) and oxaliplatin (OXA)) can elicit antitumor immune response by promoting im......
Recurrence and drug resistance of acute myeloid leukemia (AML) remained the leading causes of death in blood cancers. The interaction of chemokine rec......
Innate sensing of viral RNA analogs represents a promising tool for cancer intervention, yet the tumor microenvironment (TME) renders tumor cells and ......
Bio-based nanomaterials have received considerable attention in cancer therapies due to their potent characteristics such as autologous pharmaceutical......
Immune checkpoint blockade (ICB) therapy has emerged as novel therapeutic modality for hard-to-treat solid tumors. However, inadequate T cell infiltra......
Direct intratumoral injection of aggregation-induced emission luminogen (AIEgen) enable direct photodynamic therapy (PDT) of tumors, but these injecti......