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Treatment with Methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) and the Risk of All-Cause Poisoning in Children and Adolescents: A Self-Controlled Case Series Study

期刊: CNS DRUGS, 2021; 35 (7)

Background Children and adolescents with attention deficit hyperactivity disorder (ADHD) are at higher risk of all-cause poisoning by drugs and chemic......

Erythropoietin Improves Poor Outcomes in Preterm Infants with Intraventricular Hemorrhage

期刊: CNS DRUGS, 2021; 35 (6)

Background Intraventricular hemorrhage (IVH) is a common complication in preterm infants that has poor outcomes, especially in severe cases, and there......

The Effect of Statin Treatment on Outcomes of Cardioembolic Stroke: A Systematic Review and Meta-Analysis of Real-World Studies

期刊: CNS DRUGS, 2021; 35 (7)

Background Several real-world observational studies have investigated the association between statin treatment and outcomes of cardioembolic stroke. H......

Prevention and Management of Common Adverse Effects of Ketamine and Esketamine in Patients with Mood Disorders

期刊: CNS DRUGS, 2021; 35 (9)

The emerging roles of ketamine and esketamine as effective rapid-acting antidepressants hold promise for patients suffering from treatment-resistant d......

Mortality Risk Associated with Haloperidol Use Compared with Other Antipsychotics: An 11-Year Population-Based Propensity-Score-Matched Cohort Study

期刊: CNS DRUGS, 2020; 34 (2)

Background Haloperidol remains a frequently prescribed first-generation antipsychotic. However, haloperidol-associated mortality risk by all causes, c......

Safety and Efficacy of Ubrogepant for the Acute Treatment of Episodic Migraine: A Meta-Analysis of Randomized Clinical Trials

期刊: CNS DRUGS, 2020; 34 (5)

Background Ubrogepant is a small molecular calcitonin gene-related peptide receptor antagonist that is used for the acute treatment of migraine. Objec......

Sleep Disorders in Children and Adolescents with Autism Spectrum Disorder: Diagnosis, Epidemiology, and Management

期刊: CNS DRUGS, 2020; 34 (4)

Sleep problems are a common complaint in children/adolescents with autism spectrum disorder (ASD). Correctly diagnosing and treating sleep problems in......

Application of Healthcare 'Big Data' in CNS Drug Research: The Example of the Neurological and mental health Global Epidemiology Network (NeuroGEN)

期刊: CNS DRUGS, 2020; 34 (9)

Neurological and psychiatric (mental health) disorders have a large impact on health burden globally. Cognitive disorders (including dementia) and str......

Lasmiditan for Acute Treatment of Migraine in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials

期刊: CNS DRUGS, 2020; 34 (10)

Background The US Food and Drug Administration has approved orally administered 100-mg and 200-mg doses of lasmiditan for the acute treatment of migra......

Antipsychotics and Risk of Neuroleptic Malignant Syndrome: A Population-Based Cohort and Case-Crossover Study

期刊: CNS DRUGS, 2020; 34 (11)

Background Neuroleptic malignant syndrome (NMS) is a rare and acute adverse drug reaction associated with antipsychotic therapy. However, few data on ......

Levetiracetam versus Phenytoin for the Pharmacotherapy of Benzodiazepine-Refractory Status Epilepticus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

期刊: CNS DRUGS, 2020; 34 (12)

Background Recent studies have shown conflicting results regarding the effectiveness of levetiracetam for treating benzodiazepine-refractory status ep......

Relative Seizure Relapse Risks Associated with Antiepileptic Drug Withdrawal After Different Seizure-Free Periods in Adults with Focal Epilepsy: A Prospective, Controlled Follow-Up Study

期刊: CNS DRUGS, 2019; 33 (11)

Background Approximately two-thirds of patients with newly diagnosed epilepsy become seizure-free after antiepileptic drug (AED) treatment. A crucial ......

JIF:4.19

Tranexamic Acid in Cerebral Hemorrhage: A Meta-Analysis and Systematic Review

期刊: CNS DRUGS, 2019; 33 (4)

BackgroundTranexamic acid functions as an antifibrinolytic medication and is widely used to treat or prevent excessive blood loss in menorrhagia and d......

JIF:4.19

Safety, Pharmacokinetics and Pharmacodynamics of TNHH, a Novel Targeted Neutrophil-Inhibitory Hirulog Hybrid Glycoprotein, in Healthy Volunteers

期刊: CNS DRUGS, 2019; 33 (6)

BackgroundTargeted neutrophil inhibitory-hirulog (TNHH) is a novel hybrid glycoprotein that may be a potential drug candidate for acute ischaemic stro......

JIF:4.19

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