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Clinical characteristics and potential factors for recurrence of positive SARS-CoV-2 RNA in convalescent patients: a retrospective cohort study

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Background The recurrence of positive SARS-CoV-2 RT-PCR is frequently found in discharged COVID-19 patients but its clinical significance remains uncl......

The association of transforming growth factor beta 1 gene polymorphisms with arthritis: a systematic review and meta-analysis

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (2)

The objective of this study was to explore the association between transformation growth factor beta 1 (TGF-beta 1) gene polymorphisms and different t......

Clinicopathologic findings of chronic active Epstein-Barr virus infection in adults: A single-center retrospective study in China

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Chronic active Epstein-Barr virus (CAEBV) infection is a rare disease with a high mortality rate. Our study aimed to summarize the clinicopathological......

The risk factors for early mortality and end-stage renal disease in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis: experiences from a single center

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a common disease with high mortality. Kidney involvement in AAV commonly pe......

Clinical presentation, therapeutic approach, and outcome of young patients admitted for COVID-19, with respect to the elderly counterpart

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (2)

There is limited information on the presenting characteristics, prognosis, and therapeutic approaches of young patients hospitalized for coronavirus d......

Ferroptosis-related genes are potential prognostic molecular markers for patients with colorectal cancer

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Ferroptosis is a newly discovered programmed cell death that plays a vital role in the occurrence and development of tumors. However, little is known ......

Exosomes derived from mesenchymal stem cells regulate Treg/Th17 balance in aplastic anemia by transferring miR-23a-3p

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Imbalanced Th17/Treg ratio is implicated in the pathogenesis of aplastic anemia. Studies have indicated that bone marrow-derived mesenchymal stem cell......

Overexpression of miR-1225 promotes the progression of breast cancer, resulting in poor prognosis

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (2)

Breast cancer is the most common cancer among women, with metastasis as the principal cause of mortality. MiR-1225 has been reported to play roles in ......

Effect of Activin A on activation status of monocytes in acute-phase Kawasaki disease

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

Kawasaki disease is a kind of self-limited systemic vasculitis involving middle and small arteries, which usually occurs in children under 5 years old......

REC8 promotes tumor migration, invasion and angiogenesis by targeting the PKA pathway in hepatocellular carcinoma

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (3)

REC8 is a member of the cohesin family, and its abnormal activation has been detected in cancer cells. This study explored the role and possible mecha......

A retrospective study of the risk factors and the prognosis in patients with papillary thyroid carcinoma depending on the number of lymph node metastasis

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2021; 21 (2)

To retrospectively analyze the risk factors and the prognosis according to the number of lymph node metastases (LNMs) in different neck compartments i......

Gene expression profiling revealed MCM3 to be a better marker than Ki67 in prognosis of invasive ductal breast carcinoma patients

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2020; 20 (2)

Invasive ductal carcinoma (IDC) is the most common breast cancer. Our study used gene microarray data to select differentially expressed genes between......

The role of fibroblast activation protein in progression and development of osteosarcoma cells

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2020; 20 (1)

To investigate the expression levels of fibroblast activation protein (FAP) in human osteosarcoma tissues and its possible correlations with clinical ......

E3 ubiquitin ligase CHIP attenuates cellular proliferation and invasion abilities in triple-negative breast cancer cells

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2020; 20 (1)

Carboxyl terminus of Hsc-70-interacting protein (CHIP), as U-box-type ubiquitin ligase, connects the chaperone and proteasome systems and plays a pivo......

Diagnostic value of seven biomarkers for breast cancer: an overview with evidence mapping and indirect comparisons of diagnostic test accuracy

期刊: CLINICAL AND EXPERIMENTAL MEDICINE, 2020; 20 (1)

Several meta-analyses have evaluated the value of biomarkers in diagnosing breast cancer, but which biomarker has the optimal diagnostic value remains......

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