Background: Multiple studies over the past 4 decades have shown the significant benefit of breast cancer screening (BCS) in reducing mortality rates f......
Background: PD-1/PD-L1 inhibitors in combination with chemotherapy are widely used in clinical practice. However, the ideal combined timing of them ha......
Background: European Society for Medical Oncology Women for Oncology (ESMO W4O) research has previously shown under-representation of female oncologis......
Background: The ATLAS trial, investigating adjuvant axitinib versus placebo in renal cell carcinoma (RCC), was stopped for futility at a preplanned in......
Background: The impact of pretreatment factors on immune checkpoint inhibition in platinum-refractory advanced urothelial cancer (aUC) deserves furthe......
Background: There is no clinically applicable prognostic model designed for patients with de novo metastatic nasopharyngeal carcinoma (mNPC) treated w......
Background: Liquid biopsy based on 5-hydroxymethylcytosine (5hmC) signatures of plasma cell-free DNA (cfDNA) originating from tumor cells provides a n......
Background ERBB2 exon 16 skipping is an alternatively spliced isoform of ERBB2, which was reported to lead to oncogenic activation of ERBB2 and could ......
Background The prognostic impact of comorbidities in patients with sarcomas is not well defined. The aims of this study were to examine the implicatio......
Objective To investigate the preoperative predictive value of non-invasive imaging biomarkers for programmed cell death protein 1/programmed cell deat......
Background Monoclonal antibodies of anti-epidermal growth factor receptor (EGFR) have been recommended as first-line therapy for patients with left-si......
Objective The prediction of survival of gastric neuroendocrine tumours (g-NETs) is controversial. Prognostic effects of the metastatic lymph node rati......
During the last years, there has been a dramatic increase in the administrative and bureaucratic burden associated with clinical research, which has c......