期刊: EXPERIMENTAL HEMATOLOGY, 2022; 110 ()
CRISPR-Cas9 is a powerful tool for editing the genome and holds great promise for gene therapy applications. Initial concerns of gene engineering focu......
期刊: EXPERIMENTAL HEMATOLOGY, 2022; 105 ()
Acute myeloid leukemia (AML) remains a clinical challenge. Venetoclax is an effective Bcl-2 selective inhibitor approved by the U.S. Food and Drug Adm......
期刊: EXPERIMENTAL HEMATOLOGY, 2022; 108 ()
This study sought to clarify the role of heterogeneous nuclear ribonucleoprotein K (hnRNPK) as a regulator of imatinib resistance in Philadelphia chro......
期刊: EXPERIMENTAL HEMATOLOGY, 2022; 106 ()
Calcium (Ca2+) is an important second messenger molecule in the body, regulating cell cycle and fate. There is growing evidence that intracellular Ca2......
期刊: EXPERIMENTAL HEMATOLOGY, 2022; 114 ()
5-Aza-20-deoxycytidine (5-Aza-dC) is a demethylation agent known to deplete DNA methyltransferases (DNMTs) in leukemia cancer cells, and can restore t......
期刊: EXPERIMENTAL HEMATOLOGY, 2021; 96 ()
There is accumulating evidence suggesting that toll-like receptor (TLR) signals play an important role in the regulation of hematopoietic stem/progeni......
期刊: EXPERIMENTAL HEMATOLOGY, 2021; 96 ()
Minimal residual disease (MRD) levels monitored by polymerase chain reaction are associated with outcomes in acute myeloid leukemia with RUNX1-RUNX1T1......
期刊: EXPERIMENTAL HEMATOLOGY, 2021; 97 ()
Rpl11 haploinsufficient mice develop a macrocytic anemia similar to patients with DBA. Here, we fully characterize this model from clinical and pathop......
期刊: EXPERIMENTAL HEMATOLOGY, 2021; 94 ()
Treatment options are limited in patients with diffuse large B-cell lymphoma (DLBCL). Salvianolic acid A (SAA) is a water-soluble phenolic acid extrac......
期刊: EXPERIMENTAL HEMATOLOGY, 2020; 81 ()
Exposure of cells to bortezomib (BTZ) could activate heat shock protein (HSP) expression, which is regulated mainly by heat shock factor 1 (HSF1). We ......
期刊: EXPERIMENTAL HEMATOLOGY, 2020; 81 ()
For patients with chronic myeloid leukemia, reverse transcription quantitative polymerase chain reaction is widely used in laboratories to quantify BC......
期刊: EXPERIMENTAL HEMATOLOGY, 2020; 82 ()
The histone lysine demethylase KDM5 family is implicated in normal development and stem cell maintenance by epigenetic modulation of histone methylati......
期刊: EXPERIMENTAL HEMATOLOGY, 2020; 85 ()
Hematopoiesis refers to the developmental process generating all blood lineages. In vertebrates, there are multiple waves of hematopoiesis, which emer......
期刊: EXPERIMENTAL HEMATOLOGY, 2020; 89 ()
Autoimmune cytopenia includes autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and Evans syndrome (ES) caused by abnormal activation......