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Genetic deletion of hspa8 leads to selective tissue malformations in zebrafish embryonic development

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (21)

The heat shock cognate 71 kDa protein HSPA8 (also known as HSC70), a constitutively expressed cognate member of the heat shock protein 70 family, play......

JIF:3.907

Oligopeptide transporter Slc15A modulates macropinocytosis in Dictyostelium by maintaining intracellular nutrient status

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (7)

Macropinocytosis mediates non-selective bulk uptake of extracellular fluid. It is the major route by which axenic Dictyostelium cells obtain nutrients......

JIF:3.907

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (6)

TDP-43 (also known as TARDBP) is a nuclear splicing factor functioning in pre-mRNA processing. Its C-terminal 35-kDa fragment (TDP-35) forms inclusion......

JIF:3.907

Drp1 regulates transcription of ribosomal protein genes in embryonic hearts

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (4)

Mitochondria, dysfunction causes severe congenital cardiac abnormalities and prenatal/neonatal lethality. The lack of sufficient knowledge regarding h......

JIF:3.907

LMBR1L regulates the proliferation and migration of endothelial cells through Norrin/beta-catenin signaling

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (6)

Precise Norrin and beta-catenin (Norrin/beta-catenin; encoded by NDP and CTNNB1, respectively) signaling is critical for proper angiogenesis. Dysregul......

JIF:3.907

Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (13)

NFAT5 is the only known mammalian tonicity-responsive transcription factor with an essential role in cellular adaptation to hypertonic stress. It is a......

JIF:3.907

A genome-wide CRISPR screen identifies HuR as a regulator of apoptosis induced by dsRNA and virus

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (6)

We performed an unbiased whole-genome CRISPR/Cas9 screen in A549 cells to identify potential regulators involved in cell death triggered by double-str......

JIF:3.907

A WDR47 homolog facilitates ciliogenesis by modulating intraflagellar transport

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (24)

Cilia are conserved organelles found in many cell types in eukaryotes, and their dysfunction causes defects in environmental sensing and signaling tra......

JIF:3.907

Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (9)

In the trunk of developing zebrafish embryos, adjacent myotome blocks transmit contractile force via myoseptal junctions (MJs), which are dynamic stru......

JIF:3.907

FCHSD2 is required for stereocilia maintenance in mouse cochlear hair cells

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (16)

Stereocilia are F-actin-based protrusions on the apical surface of inner-ear hair cells and are indispensable for hearing and balance perception. The ......

JIF:3.907

AMBRA1 promotes dsRNA- and virus-induced apoptosis through interacting with and stabilizing MAVS

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (1)

Apoptosis is an important cellular response to viral infection. In this study, we identified activating molecule in Beclin1-regulated autophagy protei......

JIF:3.907

Platelet-derived microvesicles regulate vascular smooth muscle cell energy metabolism via PRKAA after intimal injury

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (7)

Vascular intimal injury initiates various cardiovascular disease processes. Exposure to subendothelial collagen can cause platelet activation, leading......

JIF:3.907

An atypical MAPK regulates translocation of a GATA transcription factor in response to chemoattractant stimulation

期刊: JOURNAL OF CELL SCIENCE, 2022; 135 (16)

The Dictyostelium atypical mitogen-activated protein kinase (MAPK) Erk2 is required for chemotactic responses to cAMP as amoeba undergo multicellular ......

JIF:3.907

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