期刊: CLINICAL PHARMACOKINETICS, 2021; 60 (5)
Drug metabolism is a critical process for the removal of unwanted substances from the body. In humans, approximately 80% of oxidative metabolism and a......
期刊: CLINICAL PHARMACOKINETICS, ; ()
Objective The aim of this systematic review and meta-analysis was to compare the clinical outcomes between genotype-guided and conventional tacrolimus......
期刊: CLINICAL PHARMACOKINETICS, ; ()
Background and Objective Fetal circulation is unique and the parameters describing hemodynamic status during development are critical for constructing......
期刊: CLINICAL PHARMACOKINETICS, ; ()
Background and Objective Thyroid eye disease (TED) is characterized by inflammation/expansion of orbital tissues, proptosis, and diplopia. Teprotumuma......
期刊: CLINICAL PHARMACOKINETICS, 2021; 60 (3)
Background: Levetiracetam has been widely used as a treatment option for different types of epilepsy in both adults and children. Because of its large......
期刊: CLINICAL PHARMACOKINETICS, 2020; 59 (4)
BackgroundDevelopmental physiology can alter pharmacotherapy in preterm populations. Because of ethical and clinical constraints in studying this vuln......
期刊: CLINICAL PHARMACOKINETICS, 2020; 59 (8)
The interchangeability evaluation for generic drugs formulated as intravenous injections normally only requires assessments of pharmaceutical equivale......
期刊: CLINICAL PHARMACOKINETICS, 2019; 58 (4)
ObjectiveThe aim of this study was to measure and investigate correlations of lamotrigine concentrations in maternal as well as umbilical cord blood, ......
期刊: CLINICAL PHARMACOKINETICS, 2019; 58 (6)
Numerous population pharmacokinetic studies on voriconazole have been conducted in recent years. This review aimed to comprehensively summarize the po......
期刊: CLINICAL PHARMACOKINETICS, 0; ()
Background Preterm neonates are usually not part of a traditional drug development programme, however they are frequently administered medicines. Deve......
期刊: CLINICAL PHARMACOKINETICS, 2019; 58 (3)
Objectives The aim of this study was to assess the pharmacokinetics (PK) and safety/tolerability of siponimod in healthy subjects when coadministered ......
期刊: CLINICAL PHARMACOKINETICS, 2019; 58 (7)
BackgroundThe vast majority of physiological and biological data required for physiologically based predictions are primarily available in Caucasians ......