期刊: DEVELOPMENT, 2022; 149 (13)
KDM6B-mediated epigenetic modification of the testicular regulator Dmrtl has previously been identified as the primary switch of the male pathway in a......
期刊: DEVELOPMENT, 2022; 149 (7)
Beige adipocytes have a discrete developmental origin and possess notable plasticity in their thermogenic capacity in response to various environmenta......
期刊: DEVELOPMENT, 2022; 149 (10)
Recent evidence has shown that presenilin enhancer 2 (Pen2; Psenen) plays an essential role in corticogenesis by regulating the switch of apical proge......
期刊: DEVELOPMENT, 2022; 149 (16)
In vertebrates, hematopoietic stem and progenitor cells (HSPCs) are capable of self-renewal and continuously replenishing all mature blood lineages th......
期刊: DEVELOPMENT, 2022; 149 (2)
A long-standing view in the field of evo-devo is that insect forewings develop without any Hox gene input. The Hox gene Antennapedia (Antp), despite b......
期刊: DEVELOPMENT, 2022; 149 (6)
The mitochondrial matrix AAA(+) Lon protease (LONP1) degrades misfolded or unassembled proteins, which play a pivotal role in mitochondrial quality co......
期刊: DEVELOPMENT, 2022; 149 (23)
Developmentally, the great vessels of the heart originate from the pharyngeal arch arteries (PAAs). During PAA vasculogenesis, PAA precursors undergo ......
期刊: DEVELOPMENT, 2022; 149 (3)
The tracheal epithelium is a primary target for pulmonary diseases as it provides a conduit for air flow between the environment and the lung lobes. T......
期刊: DEVELOPMENT, 2022; 149 (5)
Mammalian oocyte maturation is a unique asymmetric division, which is mainly because of actin-based spindle migration to the cortex. In the present st......
期刊: DEVELOPMENT, 2022; 149 (17)
Stomata are epidermal pores that control gas exchange between plants and the atmosphere. In Arabidopsis, the ERECTA family (ERECTAf) receptors, includ......
期刊: DEVELOPMENT, 2022; 149 (17)
Mutations that occur in RNA-splicing machinery may contribute to hematopoiesis-related diseases. How splicing factor mutations perturb hematopoiesis, ......
期刊: DEVELOPMENT, 2022; 149 (17)
tRNA synthetase deficiency leads to unfolded protein responses in neuronal disorders; however, its function in embryonic neurogenesis remains unclear.......
期刊: DEVELOPMENT, 2022; 149 (10)
Adventitious roots (ARs) are an important type of plant root and display high phenotypic plasticity in response to different environmental stimuli. It......
期刊: DEVELOPMENT, 2022; 149 (10)
Mammalian early embryo cells have complex DNA repair mechanisms to maintain genomic integrity, and homologous recombination (HR) plays the main role i......
期刊: DEVELOPMENT, 2022; 149 (13)
After ischemic stroke, promotion of vascular regeneration without causing uncontrolled vessel growth appears to be the major challenge for pro-angioge......