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Intraoperative Quantitative Measurements for Bradykinesia Evaluation during Deep Brain Stimulation Surgery Using Leap Motion Controller: A Pilot Study

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Deep brain stimulation (DBS) has shown a remarkably high effectiveness for Parkinson's disease (PD). In many PD patients during DBS surgery, the thera......

Effect of NTN and Lmx1 alpha on the Notch Signaling Pathway during the Differentiation of Human Bone Marrow Mesenchymal Stem Cells into Dopaminergic Neuron-Like Cells

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Human bone marrow mesenchymal stem cells (h-BMSCs) have the potential to differentiate into dopaminergic neuron-like cells to treat Parkinson's diseas......

Transcranial Sonography of the Substantia Nigra for the Differential Diagnosis of Parkinson's Disease and Other Movement Disorders: A Meta-Analysis

期刊: PARKINSONS DISEASE, 2021; 2021 ()

This meta-analysis aimed to evaluate the accuracy of hyperechogenicity of the substantia nigra (SN) for the differential diagnosis of Parkinson's dise......

Quantitative Analysis of Postural Instability in Patients with Parkinson's Disease

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Introduction. Postural instability is commonly observed in Parkinson's disease, leading to an increasing risk of falling and worsening as the disease ......

Altered Regional Homogeneity and Functional Connectivity during Microlesion Period after Deep Brain Stimulation in Parkinson's Disease

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Background. Patients with Parkinson's disease (PD) undergoing deep brain electrode implantation experience a temporary improvement in motor symptoms b......

Delirium after Deep Brain Stimulation in Parkinson's Disease

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Deep brain stimulation is a primary treatment method that improves motor and motor complications in patients with advanced Parkinson's disease. Deliri......

CUB and Sushi Multiple Domains (CSMD1) Gene Polymorphisms and Susceptibilities to Idiopathic Parkinson's Disease in Northern Chinese Han Population: A Case-Control Study

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Evidence has shown that the CUB and Sushi Multiple Domains (CSMD1) gene is an inhibitor of the complement activation pathway and is also involved in c......

Abnormal Gray Matter Volume and Functional Connectivity Parkinson's Disease with Rapid Eye Movement Sleep Behavior Disorder

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Objective. Rapid eye movement (REM) sleep behavior disorder (RBD) is a common symptom in Parkinson's disease (PD), and patients with PD-RBD tend to ha......

Efficacy and Safety of Pramipexole Sustained Release versus Immediate Release Formulation for Nocturnal Symptoms in Chinese Patients with Advanced Parkinson's Disease: A Pilot Study

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Objective. To explore the efficacy and safety of pramipexole sustained release (SR) versus pramipexole immediate release (IR) in treating nocturnal sy......

The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type

期刊: PARKINSONS DISEASE, 2021; 2021 ()

Objectives. To observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson's disease (PD) and multiple system ......

Urinary Dysfunction Is Associated with Nigrostriatal Dopaminergic Degeneration in Early and Untreated Patients with Parkinson's Disease

期刊: PARKINSONS DISEASE, 2020; 2020 ()

The aim of the present study was to determine the relation between urinary dysfunction and nigrostriatal dopaminergic degeneration in early and untrea......

Freezing More than Gait: A Case Report of Freezing of Urination (FOU) in Parkinson's Disease

期刊: PARKINSONS DISEASE, 2020; 2020 ()

Freezing of gait (FOG) is a disabling phenomenon that is described by patients with Parkinson's disease (PD). Not only gait may be involved in the fre......

Phosphorylated Alpha-Synuclein in Red Blood Cells as a Potential Diagnostic Biomarker for Multiple System Atrophy: A Pilot Study

期刊: PARKINSONS DISEASE, 2020; 2020 ()

Diagnosis of multiple system atrophy (MSA) remains a challenge, due to the complexity and overlapping of its symptoms with other Parkinsonian disorder......

Can the Executive Control Network be Used to Diagnose Parkinson's Disease and as an Efficacy Indicator of Deep Brain Stimulation?

期刊: PARKINSONS DISEASE, 2020; 2020 ()

Objective. The aim of this work was to investigate whether there are differences in the executive control network (ECN) between patients with Parkinso......

Validation of Revised Chinese Version of PD-CRS in Parkinson's Disease Patients

期刊: PARKINSONS DISEASE, 2020; 2020 ()

t There is a high prevalence of mild cognitive impairment (MCI) and dementia in Parkinson's disease (PD) patients, but a Chinese version of cognitive ......

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