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Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (12)

Blockade of immune checkpoints as a strategy of cancer cells to overcome the immune response has received ample attention in cancer research recently.......

JIF:21.224

Rapid and efficient isolation platform for plasma extracellular vesicles: EV-FISHER

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (11)

Extracellular vesicles (EVs) have found diverse applications in clinical theranostics. However, the current techniques to isolate plasma EVs suffer fr......

JIF:21.224

Untouched isolation enables targeted functional analysis of tumour-cell-derived extracellular vesicles from tumour tissues

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (4)

To accurately identify the functions of tumour-cell-derived extracellular vesicles (T-EVs), EVs directly isolated from tumour tissues are much preferr......

JIF:21.224

Biosynthetic neoantigen displayed on bacteria derived vesicles elicit systemic antitumour immunity

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (12)

Neoantigens derived from mutant proteins in tumour cells could elicit potent personalized anti-tumour immunity. Nevertheless, the layout of vaccine ve......

JIF:21.224

Proteomic analysis of MSC-derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (7)

Apoptotic vesicles (apoVs) are apoptotic cell-derived nanosized vesicles that play a crucial role in multiple pathophysiological settings. However, th......

JIF:21.224

Extracellular vesicles from lung tissue drive bone marrow neutrophil recruitment in inflammation

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (5)

Extracellular vesicles (EVs) are single-membrane vesicles that play an essential role in long-range intercellular communications. EV investigation has......

JIF:21.224

CD73 in small extracellular vesicles derived from HNSCC defines tumour-associated immunosuppression mediated by macrophages in the microenvironment

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (5)

Research on tumour cell-derived small extracellular vesicles (sEVs) that regulate tumour microenvironment (TME) has provided strategies for targeted t......

JIF:21.224

Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (8)

Glioma is one of the primary malignant brain tumours in adults, with a poor prognosis. Pharmacological reagents targeting glioma are limited to achiev......

JIF:21.224

Tumour-derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour-homing and intracellular freeway transportation

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (3)

Extracellular vesicles (EVs) have been proved a promising small interfering RNA (siRNA) delivery vehicle to mediate gene-silencing. Tumour-derived ext......

JIF:21.224

Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (4)

Immune checkpoint inhibitor (ICI)-based immunotherapy brought new hope for gastric cancer (GC) treatment. However, due to the lack of proper biomarker......

JIF:21.224

Extracellular vesicles enclosed-miR-421 suppresses air pollution (PM2.5) induced cardiac dysfunction via ACE2 signalling

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (5)

Air pollution, via ambient PM2.5, is a big threat to public health since it associates with increased hospitalisation, incidence rate and mortality of......

JIF:21.224

Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway

期刊: JOURNAL OF EXTRACELLULAR VESICLES, 2022; 11 (9)

Pattern-recognition receptors (PRRs) have been shown to promote tumour metastasis via sensing tumour cell-derived small extracellular vesicles (EVs). ......

JIF:21.224

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