期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)
A precondition for efficient proinsulin export from the endoplasmic reticulum (ER) is that proinsulin meets ER quality control folding requirements, i......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)
Diabetic retinopathy (DR) is the leading cause of vision loss in working adults in developed countries. The disease traditionally classified as a micr......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (14)
Within an articulately characterized family of ion channels, the voltage-gated sodium channels, exists a black sheep, SCN7A (Na-x). Na-x, in contrast ......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (15)
Human induced pluripotent stem cells (iPSCs) technology has been widely applied to cell regeneration and disease modeling. However, most mechanism of ......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)
Substance use disorder (SUD) is a growing health problem that affects several millions of people worldwide, resulting in negative socioeconomic impact......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (6)
BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on the way to be a hotspot of research with its physiological and patholog......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (15)
Acute kidney injury (AKI) is one of the most common clinical syndromes. AKI is associated with significant morbidity and subsequent chronic kidney dis......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)
Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat to human health. Flaviviruses replicate in compartmentaliz......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (17-18)
Pancreatic cancer (PC) is a kind of common digestive system cancer with the worst prognosis for its insidious symptoms and high invasiveness. Circular......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (17-18)
Ischemic stroke is one of the most serious diseases today, and only a minority of patients are provided with effective clinical treatment. Importantly......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (12)
Mammalian lungs are metabolically active organs that frequently encounter environmental insults. Stress responses elicit protective autophagy in epith......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)
Hematopoietic stem cells (HSCs) perceive both soluble signals and biomechanical inputs from their microenvironment and cells themselves. Emerging as c......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)
Emerging evidence shows that m(6)A, one of the most abundant RNA modifications in mammals, is involved in the entire process of spermatogenesis, inclu......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (10)
Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer's disease (AD). Along AD progressi......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (12)
Rheumatoid arthritis (RA) is a chronic autoimmune disease with joint and systemic inflammation that is accompanied by the production of autoantibodies......