期刊： TRENDS IN IMMUNOLOGY, 2021; 42 (8)
T cell receptor (TCR) beta-selection (herein referred to as beta-selection) is a pivotal checkpoint in mammalian T cell development when immature CD4-......
期刊： TRENDS IN IMMUNOLOGY, 2021; 42 (6)
Sepsis and septic shock driven by microbial infections are still among the most challenging health problems, causing 11 million deaths worldwide every......
期刊： TRENDS IN IMMUNOLOGY, 2021; 42 (1)
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the dramatic elevation of interleukin 10 (IL-10). This was thought to......
期刊： TRENDS IN IMMUNOLOGY, 2021; 42 (2)
Mammalian T cell development initiates from the migration of hematopoietic progenitors to the thymus, which undergo cell proliferation, T-lineage spec......
期刊： TRENDS IN IMMUNOLOGY, 2020; 41 (2)
Members of the nuclear receptor (NR) superfamily orchestrate cellular processes that can impact on numerous cancer hallmarks. NR activity plays import......
期刊： TRENDS IN IMMUNOLOGY, 2020; 41 (4)
The enzyme type HA secreted phospholipase A2 (sPLA2-IIA) is crucial for mammalian innate host defense against bacterial pathogens. Most studies have i......
期刊： TRENDS IN IMMUNOLOGY, 2020; 41 (5)
Coronavirus (CoV) disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS)-CoV-2 (also known as 2019-nCoV) is threatening global pub......
期刊： TRENDS IN IMMUNOLOGY, 2020; 41 (6)
Host circadian rhythmicity and the timing of feeding are increasingly recognized to cross-regulate and entrain each other, and may play crucial roles ......
期刊： TRENDS IN IMMUNOLOGY, 2020; 41 (11)
Food sensitivities are on the rise worldwide. Peripheral induced regulatory T cells (pTreg cells) play a central role in oral tolerance to dietary ant......
期刊： TRENDS IN IMMUNOLOGY, 2019; 40 (4)
Several T cell-boosting anticancer therapies (including anti-CD19 CAR-T cells and bi-specific T cell engagers, BiTEs) have been approved by the FDA fo......
期刊： TRENDS IN IMMUNOLOGY, 2019; 40 (12)
Inflammation benefits the host by promoting the elimination of invading pathogens and clearance of cellular debris after tissue injury. Inflammation a......
期刊： TRENDS IN IMMUNOLOGY, 2019; 40 (12)
T cell receptor (TCR) ligand discovery is crucial to monitoring T cell responses to antigen and to identifying antigens reactive against orphan TCRs o......
期刊： TRENDS IN IMMUNOLOGY, 2018; 39 (5)
The assembly of the NLRP3 inflammasome can promote the release of IL-1 beta/IL-18 and initiate pyroptosis. Accordingly, the dysregulation of NLRP3 inf......
