期刊： BIOMARKER RESEARCH, 2021; 9 (1)
N6-methyladenosine (m(6)A) is a prevalent internal RNA modification in higher eukaryotic cells. As the pivotal m(6)A regulator, RNA methyltransferase-......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Acute myeloid leukemia (AML) is a hematologic malignancy with an unfavorable prognosis. A better understanding of AML pathogenesis and chemotherapy re......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Host-tumor immune interactions play critical roles in the natural history of tumors, including oncogenesis, progress and metastasis. On the one hand, ......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Y Venetoclax (VEN) plus azacitidine has become the first-line therapy for elderly patients with acute myeloid leukemia (AML), and has a complete remis......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
N6-methyladenosine (m6A) modification is the most prevalent internal mRNA modification and is involved in many biological processes in eukaryotes. Acc......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
It has been suggested that the heterogeneity of TAAs in lung cancer may affect the therapeutic response and disease progression. Up to now, several tu......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Primary central nervous system (CNS) lymphoma (PCNSL) is a rare type of extranodal lymphoma exclusively involving the CNS at the onset, with diffuse l......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Myelodysplastic syndrome (MDS) is an aggressive and genetically heterogeneous disease with poor prognosis. Cellular immune disorder is a common charac......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Immunomodulatory drugs (IMiDs) include thalidomide, lenalidomide, and pomalidomide, which have shown significant efficacy in the treatment of multiple......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Background: Dalpiciclib (SHR6390) is a novel inhibitor of cyclin-dependent kinase 4/6 which demonstrated promising anti-tumor potency in preclinical m......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
The myristoylated alanine-rich C-kinase substrate (MARCKS) protein has been at the crossroads of multiple signaling pathways that govern several criti......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
T cell-based immunotherapies have revolutionized treatment paradigms in various cancers, however, limited response rates secondary to lack of signific......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Deubiquitinases (DUBs) are enzymes that control the stability, interactions or localization of most cellular proteins by removing their ubiquitin modi......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Myelodysplastic syndrome with myelofibrosis (MDS-MF) has been associated with an inferior prognosis compared with MDS without MF. However, MDS-MF is n......
期刊： BIOMARKER RESEARCH, 2021; 9 (1)
Background Every year around the world, more than 2 million women are diagnosed with breast cancer and genital tract cancers. However, there are rare ......
